Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Probiotic Nutrient Moisturizer Versus Neogen Probiotics Relief Cream

Paula's Choice Probiotic Nutrient Moisturizer Versus Neogen Probiotics Relief Cream Detailed comparison of Paula's Choice Probiotic Nutrient Moisturizer versus Neogen Probiotics Relief Cream. This barrier-repair moisturizer is formulated around Lactobacillus F

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Paula's Choice Probiotic Nutrient Moisturizer Versus Neogen Probiotics Relief Cream Detailed comparison of Paula's Choice Probiotic Nutrient Moisturizer versus Neogen Probiotics Relief Cream. This barrier-repair moisturizer is formulated around Lactobacillus Ferment and Bifida Ferment Lysate to strengthen the skin barrier and hydrate skin. This calming moisturizer is formulated around Lactobacillus Ferment Lysate and Niacinamide to calm redness and strengthen the skin barrier. Water Isoamyl Laurate Glycerin Butylene Glycol Sodium Polyacrylate Starch Cetyl Alcohol Lauroyl Lysine Lactobacillus/Rye Flour Ferment Lactobacillus Ferment Bifida Ferment Lysate Glucomannan Saccharomyces Lysate Leuconostoc/Radish Root Ferment Filtrate Glycine Soja Seed Extract Camellia Sinensis Leaf Extract Tetrahexyldecyl Ascorbate Acetyl Hexapeptide-1 Palmitoyl Dipeptide-10 Ceramide Ng Orbignya Oleifera Seed Oil Palmitoyl Proline Glycine Serine Threonine Alanine Valine Arginine Proline Lysine Hcl Rubus Idaeus Fruit Extract Niacinamide Adenosine Lecithin Phytic Acid Yeast Extract Faex Tocopherol Sodium PCA Sodium Lactate PCA Magnesium Palmitoyl Glutamate Sodium Palmitoyl Sarcosinate Isopropyl Palmitate Glutamic Acid Betaine Glyceryl Stearate Hydroxyacetophenone Sodium Acrylates Copolymer Ceteth-20 Steareth-20 Polysorbate 20 PEG-75 Stearate Caprylyl Glycol Propylene Glycol 1,2-Hexanediol Phenoxyethanol Ethylhexylglycerin Water, Isoamyl Laurate, Glycerin, Butylene Glycol, Sodium Polyacrylate Starch, Cetyl Alcohol, Lauroyl Lysine, Lactobacillus/Rye Flour Ferment, Lactobacillus Ferment, Bifida Ferment Lysate, Glucomannan, Saccharomyces Lysate, Leuconostoc/Radish Root Ferment Filtrate, Glycine Soja Seed Extract, Camellia Sinensis Leaf Extract, Tetrahexyldecyl Ascorbate, Acetyl Hexapeptide-1, Palmitoyl Dipeptide-10, Ceramide Ng, Orbignya Oleifera Seed Oil, Palmitoyl Proline, Glycine, Serine, Threonine, Alanine, Valine, Arginine, Proline, Lysine Hcl, Rubus Idaeus Fruit Extract, Niacinamide, Adenosine, Lecithin, Phytic Acid, Yeast Extract, Faex, Tocopherol, Sodium PCA, Sodium Lactate, PCA, Magnesium Palmitoyl Glutamate, Sodium Palmitoyl Sarcosinate, Isopropyl Palmitate, Glutamic Acid, Betaine, Glyceryl Stearate, Hydroxyacetophenone, Sodium Acrylates Copolymer, Ceteth-20, Steareth-20, Polysorbate 20, PEG-75 Stearate, Caprylyl Glycol, Propylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Ethylhexylglycerin Lactobacillus Ferment Lysate 14.3% Propanediol Isopentyldiol Dimethicone Cyclopentasiloxane Hydrogenated Poly(C6-14 Olefin) Cyclohexasiloxane PEG-240/Hdi Copolymer Bis-Decyltetradeceth-20 Ether Butyrospermum Parkii Butter Polyglyceryl-10 Myristate Polyglyceryl-2 Stearate Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Stearyl Alcohol Allantoin Trehalose Panthenol Gossypium Herbaceum Extract Aspartic Acid Streptococcus Thermophilus Ferment Caprylic/Capric Triglyceride Royal Jelly Extract Milk Extract Propolis Extract Hydrolyzed Collagen Lactose Artemisia Capillaris Extract Simmondsia Chinensis Seed Oil Helianthus Annuus Seed Oil Isoleucine Phenylalanine Histidine Hyaluronic Acid Lupinus Albus Seed Extract Sodium Ascorbyl Phosphate Phospholipids Phytosphingosine Copper Tripeptide-1 Ceramide NP Lactic Acid Cholesterol Hydrolyzed Hyaluronic Acid Madecassoside Sodium Hyaluronate Squalane Tripeptide-1 Palmitoyl Tripeptide-1 Tripeptide-2 Hexapeptide-11 Phytosterols Dunaliella Salina Extract Acetyl Hexapeptide-8 Palmitoyl Tetrapeptide-7 Palmitoyl P These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin. Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources. It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy. Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces. A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks. Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis. One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studi