Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Resist Barrier Repair Moisturizer with Retinol Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer

Paula's Choice Resist Barrier Repair Moisturizer with Retinol Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer Detailed comparison of Paula's Choice Resist Barrier Repair Moisturizer with Retinol versus Paula's Choice Clinical Ceramide-Enri

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Paula's Choice Resist Barrier Repair Moisturizer with Retinol Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer Detailed comparison of Paula's Choice Resist Barrier Repair Moisturizer with Retinol versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer. This barrier-repair moisturizer is formulated around Retinol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This anti-aging moisturizer is formulated around Sodium Ascorbyl Phosphate and Retinol to soften the look of wrinkles and strengthen the skin barrier. Water Dicaprylyl Carbonate Glycerin Ethylhexyl Stearate Cocoglycerides Butyrospermum Parkii Butter Squalane Sodium Polyacrylate Lecithin Adenosine Palmitoyl Tripeptide-1 Ceramide NP Retinol Punica Granatum Extract Camellia Oleifera Leaf Extract Glycyrrhiza Glabra Root Extract Tetrahydrodiferuloylmethane Tetrahydrodemethoxydiferuloylmethane Tetrahydrobisdemethoxydiferuloylmethane Tocopheryl Acetate Chamomilla Recutita Flower Extract Glycine Soja Seed Extract Glycine Soja Oil Butylene Glycol Propylene Glycol Glyceryl Polymethacrylate Xanthan Gum Phenoxyethanol Water, Dicaprylyl Carbonate, Glycerin, Ethylhexyl Stearate, Cocoglycerides, Butyrospermum Parkii Butter, Squalane, Sodium Polyacrylate, Lecithin, Adenosine, Palmitoyl Tripeptide-1, Ceramide NP, Retinol, Punica Granatum Extract, Camellia Oleifera Leaf Extract, Glycyrrhiza Glabra Root Extract, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Tocopheryl Acetate, Chamomilla Recutita Flower Extract, Glycine Soja Seed Extract, Glycine Soja Oil, Butylene Glycol, Propylene Glycol, Glyceryl Polymethacrylate, Xanthan Gum, Phenoxyethanol Sodium Ascorbyl Phosphate Cetyl Alcohol Neopentyl Glycol Diheptanoate Potassium Cetyl Phosphate Glyceryl Stearate PEG-100 Stearate PEG-12 Glyceryl Dimyristate Bis-Diglyceryl Polyacyladipate-2 Dimethicone Glyceryl Ascorbate Tetrahexyldecyl Ascorbate Ceramide Ns Ceramide AP Ceramide EOP Ceramide Eos Cholesterol Caprooyl Phytosphingosine Caprooyl Sphingosine Pongamia Glabra Seed Oil Glycyrrhiza Glabra Root Vitis Vinifera Carnosine Panthenol Sodium PCA Sodium Citrate Ceteareth-25 Polysorbate 20 Sodium Hydroxide Trideceth-6 Propyl Gallate Ammonium Acryloyldimethyltaurate/Vp Copolymer Behenic Acid Disodium EDTA Caprylyl Glycol Chlorphenesin Water, Sodium Ascorbyl Phosphate, Cetyl Alcohol, Neopentyl Glycol Diheptanoate, Potassium Cetyl Phosphate, Glyceryl Stearate, PEG-100 Stearate, Glycerin, PEG-12 Glyceryl Dimyristate, Bis-Diglyceryl Polyacyladipate-2, Dimethicone, Glyceryl Ascorbate, Tetrahexyldecyl Ascorbate, Retinol, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide EOP, Ceramide Eos, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Squalane, Punica Granatum Extract, Pongamia Glabra Seed Oil, Glycyrrhiza Glabra Root, Vitis Vinifera, Tocopheryl Acetate, Carnosine, Panthenol, Sodium PCA, Butylene Glycol, Sodium Citrate, Ceteareth-25, Polysorbate 20, Ethylhexyl Stearate, Sodium Hydroxide, Trideceth-6, Propyl Gallate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Polyacrylate, Behenic Acid, Disodium EDTA, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Ethylhexyl Stearate mainly acts as an emollient that helps hydate skin. It can also be used to reduce the greasiness of oils in a formula. Because this ingredient contains a C18 fatty acid chain, it may not be Malassezia/fungal acne safe. This is because the Malassezia yeast potentially feeds on C11-C24 fatty acids. This ingredient is an ester of 2-ethylhexyl alcohol and stearic acid. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria,