Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Resist Barrier Repair Moisturizer with Retinol Versus Skinfix Barrier+ Skin Barrier Restoring Gel Cream

Paula's Choice Resist Barrier Repair Moisturizer with Retinol Versus Skinfix Barrier+ Skin Barrier Restoring Gel Cream Detailed comparison of Paula's Choice Resist Barrier Repair Moisturizer with Retinol versus Skinfix Barrier+ Skin Barrier Restoring Gel Cream

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Paula's Choice Resist Barrier Repair Moisturizer with Retinol Versus Skinfix Barrier+ Skin Barrier Restoring Gel Cream Detailed comparison of Paula's Choice Resist Barrier Repair Moisturizer with Retinol versus Skinfix Barrier+ Skin Barrier Restoring Gel Cream US. This barrier-repair moisturizer is formulated around Retinol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin. Water Dicaprylyl Carbonate Glycerin Ethylhexyl Stearate Cocoglycerides Butyrospermum Parkii Butter Squalane Sodium Polyacrylate Lecithin Adenosine Palmitoyl Tripeptide-1 Ceramide NP Retinol Punica Granatum Extract Camellia Oleifera Leaf Extract Glycyrrhiza Glabra Root Extract Tetrahydrodiferuloylmethane Tetrahydrodemethoxydiferuloylmethane Tetrahydrobisdemethoxydiferuloylmethane Tocopheryl Acetate Chamomilla Recutita Flower Extract Glycine Soja Seed Extract Glycine Soja Oil Butylene Glycol Propylene Glycol Glyceryl Polymethacrylate Xanthan Gum Phenoxyethanol Water, Dicaprylyl Carbonate, Glycerin, Ethylhexyl Stearate, Cocoglycerides, Butyrospermum Parkii Butter, Squalane, Sodium Polyacrylate, Lecithin, Adenosine, Palmitoyl Tripeptide-1, Ceramide NP, Retinol, Punica Granatum Extract, Camellia Oleifera Leaf Extract, Glycyrrhiza Glabra Root Extract, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Tocopheryl Acetate, Chamomilla Recutita Flower Extract, Glycine Soja Seed Extract, Glycine Soja Oil, Butylene Glycol, Propylene Glycol, Glyceryl Polymethacrylate, Xanthan Gum, Phenoxyethanol Propanediol Jojoba Oil/Macadamia Seed Oil Esters Triheptanoin Niacinamide Saccharide Isomerate Ammonium Acryloyldimethyltaurate/Vp Copolymer Squalene Zinc PCA Hydrolyzed Hyaluronic Acid Camellia Sinensis Seed Extract Allantoin Phytosteryl Macadamiate Phytosterols Acetyl Glutamine Caprylyl Glycol Amylopectin Sodium Hyaluronate Folic Acid Oligopeptide-3 Bacillus/Soybean Ferment Extract Oligopeptide-1 Oligopeptide-2 Hexapeptide-11 Tocopherol Lithothamnion Calcareum Extract Lactic Acid Glucose Acetyl Heptapeptide-4 C14-22 Alcohols C12-20 Alkyl Glucoside Ethylhexylglycerin Trisodium Ethylenediamine Disuccinate Potassium Sorbate Citric Acid Sodium Citrate Pentylene Glycol Sodium Benzoate Water, Squalane, Propanediol, Jojoba Oil/Macadamia Seed Oil Esters, Triheptanoin, Niacinamide, Saccharide Isomerate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Squalene, Zinc PCA, Hydrolyzed Hyaluronic Acid, Glycerin, Camellia Sinensis Seed Extract, Allantoin, Phytosteryl Macadamiate, Phytosterols, Acetyl Glutamine, Lecithin, Caprylyl Glycol, Amylopectin, Sodium Hyaluronate, Folic Acid, Oligopeptide-3, Bacillus/Soybean Ferment Extract, Oligopeptide-1, Oligopeptide-2, Hexapeptide-11, Tocopherol, Lithothamnion Calcareum Extract, Lactic Acid, Glucose, Acetyl Heptapeptide-4, C14-22 Alcohols, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate, Potassium Sorbate, Citric Acid, Sodium Citrate, Pentylene Glycol, Sodium Benzoate, Xanthan Gum, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum). It is an emollient and skin conditioning agent that is able to integrate seamlessly