Paula's Choice Resist Intensive Repair Cream Versus La Roche-Posay Redermic R Intensive Anti-Aging Treatment

Paula's Choice Resist Intensive Repair Cream Versus La Roche-Posay Redermic R Intensive Anti-Aging Treatment Detailed comparison of Paula's Choice Resist Intensive Repair Cream versus La Roche-Posay Redermic R Intensive Anti-Aging Treatment. This anti-aging moisturizer is formulated around Retinol and Simmondsia Chinensis Seed Oil to soften the look of wrinkles and hydrate skin. This anti-aging treatment is formulated around Retinol and Retinyl Linoleate to soften the look of wrinkles and refine skin texture. Water Ethylhexyl Stearate Simmondsia Chinensis Seed Oil Butylene Glycol Glycerin Caprylic/Capric Triglyceride Petrolatum Cetearyl Alcohol Dimethicone Dipentaerythrityl Hexacaprylate/Hexacaprate Glyceryl Stearate Tridecyl Trimellitate PEG-100 Stearate Phenyl Trimethicone Retinol Adenosine Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Palmitoyl Tripeptide-1 Ceramide Ng Sodium Hyaluronate Magnesium Ascorbyl Phosphate Niacinamide Tocopherol Lecithin Linoleic Acid Linolenic Acid Retinyl Palmitate Glycyrrhiza Glabra Root Extract Camellia Oleifera Leaf Extract Citrullus Lanatus Fruit Extract Lens Esculenta Fruit Extract Pyrus Malus Fruit Extract Glycine Soja Sterols Tribehenin PEG-10 Phytosterol Magnesium Aluminum Silicate Sodium PCA Sodium Lactate Pullulan Xanthan Gum Sodium Hydroxide Neopentyl Glycol Dicaprylate/Dicaprate Cetearyl Glucoside Tridecyl Stearate Behenyl Alcohol Sclerotium Gum Carbomer C12-15 Alkyl Benzoate Polysorbate 20 Disodium EDTA Sorbic Acid Phenoxyethanol Chlorphenesin Benzoic Acid Water, Ethylhexyl Stearate, Simmondsia Chinensis Seed Oil, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Petrolatum, Cetearyl Alcohol, Dimethicone, Dipentaerythrityl Hexacaprylate/Hexacaprate, Glyceryl Stearate, Tridecyl Trimellitate, PEG-100 Stearate, Phenyl Trimethicone, Retinol, Adenosine, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Ceramide Ng, Sodium Hyaluronate, Magnesium Ascorbyl Phosphate, Niacinamide, Tocopherol, Lecithin, Linoleic Acid, Linolenic Acid, Retinyl Palmitate, Glycyrrhiza Glabra Root Extract, Camellia Oleifera Leaf Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Glycine Soja Sterols, Tribehenin, PEG-10 Phytosterol, Magnesium Aluminum Silicate, Sodium PCA, Sodium Lactate, Pullulan, Xanthan Gum, Sodium Hydroxide, Neopentyl Glycol Dicaprylate/Dicaprate, Cetearyl Glucoside, Tridecyl Stearate, Behenyl Alcohol, Sclerotium Gum, Carbomer, C12-15 Alkyl Benzoate, Polysorbate 20, Disodium EDTA, Sorbic Acid, Phenoxyethanol, Chlorphenesin, Benzoic Acid Isostearyl Neopentanoate Octyldodecanol Propylene Glycol Pentylene Glycol Acrylamide Sodium Ammonium Acryloyldimethyltaurate/Vp Copolymer Vp/Va Copolymer Glycine Soja Oil Triethanolamine Isohexadecane Retinyl Linoleate Capryloyl Salicylic Acid Caprylyl Glycol Polysorbate 80 Parfum Water, Isostearyl Neopentanoate, Glycerin, Octyldodecanol, Propylene Glycol, Pentylene Glycol, Acrylamide, Sodium, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Vp/Va Copolymer, Cetearyl Alcohol, Glycine Soja Oil, Triethanolamine, Isohexadecane, Sodium Hyaluronate, Retinol, Retinyl Linoleate, Adenosine, Capryloyl Salicylic Acid, Caprylyl Glycol, Polysorbate 80, Phenoxyethanol, Parfum Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier. Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient. It plays several roles in a formula: Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products. Multiple assessments have found it to be non-irritating and non-sensitizing to most people. However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers. Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy. Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans. Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients. This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain le