Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Resist Skin Restoring Moisturizer With SPF 50 Versus Neutrogena Hydro Boost Water Gel Lotion SPF 30

Paula's Choice Resist Skin Restoring Moisturizer With SPF 50 Versus Neutrogena Hydro Boost Water Gel Lotion SPF 30 Detailed comparison of Paula's Choice Resist Skin Restoring Moisturizer With SPF 50 versus Neutrogena Hydro Boost Water Gel Lotion SPF 30. This b

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Paula's Choice Resist Skin Restoring Moisturizer With SPF 50 Versus Neutrogena Hydro Boost Water Gel Lotion SPF 30 Detailed comparison of Paula's Choice Resist Skin Restoring Moisturizer With SPF 50 versus Neutrogena Hydro Boost Water Gel Lotion SPF 30. This barrier-repair moisturizer is formulated around Allantoin and Niacinamide to strengthen the skin barrier and soften the look of wrinkles. This chemical sunscreen covers most of the UV range, lighter on the deep UVA that drives aging. Butyl Methoxydibenzoylmethane 3% Homosalate 5% Ethylhexyl Methoxycinnamate 7.5% Ethylhexyl Salicylate 5% Benzophenone-3 Water Silica Glycerin Cetearyl Alcohol Dimethicone Butylene Glycol Pentylene Glycol Potassium Cetyl Phosphate Cyclopentasiloxane Pyrus Malus Fruit Extract Vp/Eicosene Copolymer Butyrospermum Parkii Butter Allantoin Niacinamide Tocopherol Glycyrrhiza Glabra Root Extract Aloe Barbadensis Leaf Juice Atractylodes Macrocephala Root Powder Avena Sativa Kernel Extract Coffea Arabica Seed Extract Portulaca Oleracea Extract Mahonia Aquifolium Root Extract Diethylhexyl Syringylidenemalonate Sarcosine Capryloyl Glycine Maltooligosyl Glucoside Cetearyl Glucoside Dimethiconol Acrylates/C10-30 Alkyl Acrylate Crosspolymer Hydrogenated Starch Hydrolysate Hexylene Glycol 4-T-Butylcyclohexanol Glyceryl Stearate PEG-100 Stearate Sodium Hydroxide Xanthan Gum Disodium EDTA Phenoxyethanol Caprylyl Glycol Ethylhexylglycerin Butyl Methoxydibenzoylmethane 3%, Homosalate 5%, Ethylhexyl Methoxycinnamate 7.5%, Ethylhexyl Salicylate 5%, Benzophenone-3, Water, Silica, Glycerin, Cetearyl Alcohol, Dimethicone, Butylene Glycol, Pentylene Glycol, Potassium Cetyl Phosphate, Cyclopentasiloxane, Pyrus Malus Fruit Extract, Vp/Eicosene Copolymer, Butyrospermum Parkii Butter, Allantoin, Niacinamide, Tocopherol, Glycyrrhiza Glabra Root Extract, Aloe Barbadensis Leaf Juice, Atractylodes Macrocephala Root Powder, Avena Sativa Kernel Extract, Coffea Arabica Seed Extract, Portulaca Oleracea Extract, Mahonia Aquifolium Root Extract, Diethylhexyl Syringylidenemalonate, Sarcosine, Capryloyl Glycine, Maltooligosyl Glucoside, Cetearyl Glucoside, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydrogenated Starch Hydrolysate, Hexylene Glycol, 4-T-Butylcyclohexanol, Glyceryl Stearate, PEG-100 Stearate, Sodium Hydroxide, Xanthan Gum, Disodium EDTA, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin Octocrylene 6% Ethylhexyl Salicylate 4% Butyl Methoxydibenzoylmethane 1.5% Acrylates/Dimethicone Copolymer Alcohol Denat. Blue 1 Lake Caprylyl Methicone Chlorphenesin Dicaprylyl Carbonate Diisopropyl Adipate Dimethicone Crosspolymer Hydrolyzed Hyaluronic Acid Hydroxyacetophenone Parfum Polyurethane-62 Sodium Acryloyldimethyltaurate/Vp Crosspolymer Tocopheryl Acetate Trideceth-6 Octocrylene 6%, Homosalate 5%, Ethylhexyl Salicylate 4%, Butyl Methoxydibenzoylmethane 1.5%, Acrylates/Dimethicone Copolymer, Alcohol Denat., Blue 1 Lake, Caprylyl Methicone, Chlorphenesin, Dicaprylyl Carbonate, Diisopropyl Adipate, Dimethicone, Dimethicone Crosspolymer, Disodium EDTA, Glycerin, Glyceryl Stearate, Hydrolyzed Hyaluronic Acid, Hydroxyacetophenone, Parfum, Pentylene Glycol, Phenoxyethanol, Polyurethane-62, Silica, Sodium Acryloyldimethyltaurate/Vp Crosspolymer, Sodium Hydroxide, Tocopheryl Acetate, Trideceth-6, Water These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm). It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation. This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent. Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation. The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries. It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity. Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Ethylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's. It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm. You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly wee