Peptide Skincare & BeautySkin science and ingredient guides

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Paula's Choice Resist Triple Active Total Repair Serum Versus Medik8 Crystal Retinal 10

Paula's Choice Resist Triple Active Total Repair Serum Versus Medik8 Crystal Retinal 10 Detailed comparison of Paula's Choice Resist Triple Active Total Repair Serum versus Medik8 Crystal Retinal 10. This anti-aging serum is formulated around Niacinamide and R

This source-based comparison does not add ratings or recommend a winner.

Paula's Choice Resist Triple Active Total Repair Serum Versus Medik8 Crystal Retinal 10 Detailed comparison of Paula's Choice Resist Triple Active Total Repair Serum versus Medik8 Crystal Retinal 10. This anti-aging serum is formulated around Niacinamide and Retinyl Propionate to soften the look of wrinkles and fade the look of dark spots. This anti-aging serum is formulated around Retinal and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Isopropyl Myristate Caprylic/Capric Triglyceride Glycerin Niacinamide Hydroxystearic Acid Oryza Sativa Bran Oil Tocotrienols Retinyl Propionate Hexylresorcinol Acrylates/C10-30 Alkyl Acrylate Crosspolymer Cetyl Alcohol Castanea Sativa Leaf Extract Hydroxyacetophenone Ceramide AP 1,2-Hexanediol Caprylyl Glycol Sodium Hydroxide Dilauryl Thiodipropionate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Phytate BHT Water, Isopropyl Myristate, Caprylic/Capric Triglyceride, Glycerin, Niacinamide, Hydroxystearic Acid, Oryza Sativa Bran Oil, Tocotrienols, Retinyl Propionate, Hexylresorcinol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetyl Alcohol, Castanea Sativa Leaf Extract, Hydroxyacetophenone, Ceramide AP, 1,2-Hexanediol, Caprylyl Glycol, Sodium Hydroxide, Dilauryl Thiodipropionate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Phytate, BHT Isododecane Cetearyl Olivate Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol PPG-12/Smdi Copolymer Sorbitan Olivate Tocopheryl Acetate Titanium Dioxide Eclipta Prostrata Extract Cyclodextrin Squalane Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Phenoxyethanol Melia Azadirachta Leaf Extract Hydroxypropyl Methylcellulose Sodium Hyaluronate Tetrahexyldecyl Ascorbate Rubus Chamaemorus Seed Oil Alumina Isostearic Acid Lecithin Polyglyceryl-3 Polyricinoleate Polyhydroxystearic Acid Stearic Acid Pentylene Glycol Retinal Moringa Oleifera Seed Oil Sodium Polyaspartate Climbazole Disodium EDTA Lonicera Japonica Flower Extract Lonicera Caprifolium Flower Extract Daucus Carota Sativa Seed Oil Ethylhexylglycerin 3-O-Ethyl Ascorbic Acid Dipteryx Odorata Bean Extract Polysorbate 60 Sorbitan Isostearate Vanilla Planifolia Fruit Extract Decylene Glycol Coumarin Water, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Titanium Dioxide, Eclipta Prostrata Extract, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Melia Azadirachta Leaf Extract, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Pentylene Glycol, Retinal, Moringa Oleifera Seed Oil, Sodium Polyaspartate, Climbazole, Disodium EDTA, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Daucus Carota Sativa Seed Oil, Ethylhexylglycerin, 3-O-Ethyl Ascorbic Acid, Dipteryx Odorata Bean Extract, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Decylene Glycol, 1,2-Hexanediol, BHT, Coumarin Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives BHT is a synthetic antioxidant and preservative. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells. As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation. The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU. However, it was recently restricted for use in the UK as of April 2024. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high con