Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

PCA Skin Hyaluronic Acid Boosting Serum Versus PURITO Centella Unscented Serum

PCA Skin Hyaluronic Acid Boosting Serum Versus PURITO Centella Unscented Serum Detailed comparison of PCA Skin Hyaluronic Acid Boosting Serum versus PURITO Centella Unscented Serum. This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate t

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PCA Skin Hyaluronic Acid Boosting Serum Versus PURITO Centella Unscented Serum Detailed comparison of PCA Skin Hyaluronic Acid Boosting Serum versus PURITO Centella Unscented Serum. This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This calming serum is formulated around Centella Asiatica Extract and Niacinamide to calm redness and strengthen the skin barrier. Water Propanediol Glycerin Niacinamide Dimethicone Hydrolyzed Yeast Extract Polyglyceryl-3 Beeswax Coconut Alkanes Phenoxyethanol Isododecane Jojoba Esters Dimethicone Crosspolymer Polysilicone-11 Sodium Hyaluronate Sodium Benzoate Carbomer Xanthan Gum Hydrolyzed Hyaluronic Acid Cetyl Alcohol Polyglyceryl-6 Distearate Sodium Lauroyl Lactylate Disodium Acetyl Glucosamine Phosphate Hydrolyzed Glycosaminoglycans Ethylhexylglycerin Sodium Hydroxide Hexylene Glycol Polygonum Bistorta Root Extract Cetyl Hydroxyethylcellulose Rosmarinus Officinalis Leaf Oil Aroma Polyglucuronic Acid Ceramide NP Hyaluronic Acid Sodium Carrageenan Ceramide AP Phytosphingosine Caprylyl Glycol Cholesterol Lecithin Maris Sal Ceramide EOP Water, Propanediol, Glycerin, Niacinamide, Dimethicone, Hydrolyzed Yeast Extract, Polyglyceryl-3 Beeswax, Coconut Alkanes, Phenoxyethanol, Isododecane, Jojoba Esters, Dimethicone Crosspolymer, Polysilicone-11, Sodium Hyaluronate, Sodium Benzoate, Carbomer, Xanthan Gum, Hydrolyzed Hyaluronic Acid, Cetyl Alcohol, Polyglyceryl-6 Distearate, Sodium Lauroyl Lactylate, Disodium Acetyl Glucosamine Phosphate, Hydrolyzed Glycosaminoglycans, Ethylhexylglycerin, Sodium Hydroxide, Hexylene Glycol, Polygonum Bistorta Root Extract, Cetyl Hydroxyethylcellulose, Rosmarinus Officinalis Leaf Oil, Aroma, Polyglucuronic Acid, Ceramide NP, Hyaluronic Acid, Sodium Carrageenan, Ceramide AP, Phytosphingosine, Caprylyl Glycol, Cholesterol, Lecithin, Maris Sal, Ceramide EOP Centella Asiatica Extract 49% Dipropylene Glycol Butylene Glycol 1,2-Hexanediol Glycereth-26 Asiaticoside Asiatic Acid Madecassic Acid Palmitoyl Hexapeptide-12 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Dipeptide-10 Arginine Sclerotium Gum Hydrolyzed Jojoba Esters Polyglyceryl-10 Myristate Panthenol Polyglyceryl-10 Laurate Hydrogenated Lecithin Camellia Sinensis Leaf Extract Pancratium Maritimum Extract Dipotassium Glycyrrhizate Disodium EDTA Adenosine Centella Asiatica Extract 49%, Water, Glycerin, Dipropylene Glycol, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Glycereth-26, Ceramide NP, Sodium Hyaluronate, Asiaticoside, Asiatic Acid, Madecassic Acid, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Dipeptide-10, Carbomer, Arginine, Sclerotium Gum, Hydrolyzed Jojoba Esters, Caprylyl Glycol, Polyglyceryl-10 Myristate, Panthenol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Camellia Sinensis Leaf Extract, Pancratium Maritimum Extract, Dipotassium Glycyrrhizate, Disodium EDTA, Adenosine These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concen