Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

PCA Skin ReBalance Versus M-61 Hydraboost Serum 2.0

PCA Skin ReBalance Versus M-61 Hydraboost Serum 2.0 Detailed comparison of PCA Skin ReBalance versus M-61 Hydraboost Serum 2.0. This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier. This hydrat

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PCA Skin ReBalance Versus M-61 Hydraboost Serum 2.0 Detailed comparison of PCA Skin ReBalance versus M-61 Hydraboost Serum 2.0. This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier. This hydrating serum is formulated around Hydrolyzed Sodium Hyaluronate and Acetyl Hexapeptide-8 to hydrate skin and strengthen the skin barrier. Water Ethylhexyl Isononanoate Glycereth-26 Butylene Glycol Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Phenoxyethanol Niacinamide Carbomer Polyisobutene Caprylyl Glycol Bisabolol Sodium Hydroxide Ethylhexylglycerin Hexylene Glycol PEG-7 Trimethylolpropane Coconut Ether Tocopheryl Acetate Oenothera Biennis Oil Borago Officinalis Seed Oil Aloe Barbadensis Leaf Juice Sodium Hyaluronate Water, Ethylhexyl Isononanoate, Glycereth-26, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Niacinamide, Carbomer, Polyisobutene, Caprylyl Glycol, Bisabolol, Sodium Hydroxide, Ethylhexylglycerin, Hexylene Glycol, PEG-7 Trimethylolpropane Coconut Ether, Tocopheryl Acetate, Oenothera Biennis Oil, Borago Officinalis Seed Oil, Aloe Barbadensis Leaf Juice, Sodium Hyaluronate Betaine Glycerin Hydrolyzed Sodium Hyaluronate Acetyl Hexapeptide-8 Acetyl Tetrapeptide-11 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Panthenol Centella Asiatica Extract Tamarindus Indica Seed Gum Sodium Lactate Citric Acid Pentylene Glycol Disodium EDTA Echinacea Angustifolia Extract Mannitol Polysorbate 20 Potassium Sorbate Sodium Benzoate Water, Betaine, Glycerin, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Panthenol, Aloe Barbadensis Leaf Juice, Centella Asiatica Extract, Tamarindus Indica Seed Gum, Sodium Lactate, Citric Acid, Pentylene Glycol, Disodium EDTA, Echinacea Angustifolia Extract, Mannitol, Carbomer, Butylene Glycol, Polysorbate 20, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf. In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes. The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing. This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin. Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury. Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C. Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base). The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes o