Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Peptides for Cosmetic Surgery Recovery Protocol Evidence Guide: Comparison Table

Before integrating any peptide into a recovery protocol, understanding mechanism, timing, and evidence strength is essential. The table below compares the three most commonly used compounds. BPC-157 VEGF upregulation, angiogenesis, cytokine reduction Days 1–21

This source-based comparison does not add ratings or recommend a winner.

  • Before integrating any peptide into a recovery protocol, understanding mechanism, timing, and evidence strength is essential. The table below compares the three most commonly used compounds.
  • BPC-157
  • VEGF upregulation, angiogenesis, cytokine reduction
  • Days 1–21 (proliferative phase)
  • 250–500 mcg daily subcutaneous
  • Animal tendon/ligament studies, no human surgical trials
  • Strongest pre-clinical wound-healing data; dosing empirical
  • TB-500
  • Actin regulation, cell migration, MMP modulation
  • Days 3–28 (proliferation and early remodeling)
  • 2–5 mg twice weekly subcutaneous
  • Cardiac and vascular repair in animals; keratinocyte migration in vitro
  • Mechanism supports wound repair; human dosing extrapolated
  • GHK-Cu
  • Collagen synthesis, TGF-β signaling, antioxidant activity
  • Weeks 3–12 (remodeling phase)
  • 1–3 mg topical or 0.5–1.5 mg subcutaneous daily
  • Human dermatology trials for photoaging; no surgical recovery trials
  • Only peptide with direct human skin data; remodeling-phase specific