Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Perricone MD Cold Plasma Plus+ The Essence Versus The Ordinary Multi Peptides + Copper Peptide 1%

Perricone MD Cold Plasma Plus+ The Essence Versus The Ordinary Multi Peptides + Copper Peptide 1% Detailed comparison of Perricone MD Cold Plasma Plus+ The Essence versus The Ordinary Multi Peptides + Copper Peptide 1%. This anti-aging essence is formulated ar

This source-based comparison does not add ratings or recommend a winner.

Perricone MD Cold Plasma Plus+ The Essence Versus The Ordinary Multi Peptides + Copper Peptide 1% Detailed comparison of Perricone MD Cold Plasma Plus+ The Essence versus The Ordinary Multi Peptides + Copper Peptide 1%. This anti-aging essence is formulated around Saccharomyces/Rice Ferment Filtrate and Niacinamide to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Lactococcus Ferment Lysate and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture. Water Saccharomyces/Rice Ferment Filtrate Glycerin Pentylene Glycol Niacinamide Butylene Glycol 1,2-Hexanediol Polysorbate 20 Dimethyl Isosorbide Chlorphenesin Copper Tripeptide-1 3-O-Ethyl Ascorbic Acid Hyaluronic Acid Sodium Phytate Sodium Citrate Carbomer Phenoxyethanol Citric Acid Phosphatidylcholine Linoleic Acid Potassium Sorbate Acetyl Hexapeptide-8 Acetyl Tetrapeptide-11 Acetyl Tetrapeptide-9 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Linolenic Acid Tocopherol Ascorbyl Palmitate Water, Saccharomyces/Rice Ferment Filtrate, Glycerin, Pentylene Glycol, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Polysorbate 20, Dimethyl Isosorbide, Chlorphenesin, Copper Tripeptide-1, 3-O-Ethyl Ascorbic Acid, Hyaluronic Acid, Sodium Phytate, Sodium Citrate, Carbomer, Phenoxyethanol, Citric Acid, Phosphatidylcholine, Linoleic Acid, Potassium Sorbate, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Linolenic Acid, Tocopherol, Ascorbyl Palmitate Lactococcus Ferment Lysate Pentapeptide-18 Palmitoyl Tripeptide-38 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Sodium Hyaluronate Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Hydroxypropyl Cyclodextrin Sodium Chloride Sodium Hydroxide Acacia Senegal Gum Xanthan Gum Sodium Benzoate Caprylyl Glycol Ethylhexylglycerin Water, Glycerin, Lactococcus Ferment Lysate, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. Citric Acid is an alpha hydroxy acid (AHA) natur