Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Versus Lancôme Rénergie H.C.F Triple Serum

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Versus Lancôme Rénergie H.C.F Triple Serum Detailed comparison of Peter Thomas Roth Peptide 21 Wrinkle Resist Serum versus Lancôme Rénergie H.C.F Triple Serum. This anti-aging serum is formulated around Tripept

This source-based comparison does not add ratings or recommend a winner.

Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Versus Lancôme Rénergie H.C.F Triple Serum Detailed comparison of Peter Thomas Roth Peptide 21 Wrinkle Resist Serum versus Lancôme Rénergie H.C.F Triple Serum. This anti-aging serum is formulated around Tripeptide-10 Citrulline and Acetyl Octapeptide-3 to soften the look of wrinkles. This anti-aging serum is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to soften the look of wrinkles and fade the look of dark spots. Water Glycerin Rosa Centifolia Flower Water Isopropyl Myristate Squalane Mannitol Butylene Glycol Natto Gum Tripeptide-10 Citrulline Acetyl Octapeptide-3 Palmitoyl Hexapeptide-12 Acetyl Tetrapeptide-11 Acetyl Hexapeptide-8 Acetyl Hexapeptide-1 Palmitoyl Oligopeptide Acetyl Tetrapeptide-9 Acetyl Tetrapeptide-2 Tripeptide-1 Palmitoyl Tetrapeptide-7 Hexapeptide-11 Dipeptide Diaminobutyroyl Benzylamide Diacetate Palmitoyl Tripeptide-5 Trifluoroacetyl Tripeptide-2 Palmitoyl Tripeptide-1 Sodium Polyglutamate Sodium Hyaluronate Tocopheryl Acetate Retinyl Palmitate Ascorbic Acid Hydrolyzed Soy Protein Hydrolyzed Wheat Protein Lecithin Pseudoalteromonas Ferment Extract Acrylates Copolymer Magnesium Chloride Polysorbate 20 Dimethyl Isosorbide Acrylates/C10-30 Alkyl Acrylate Crosspolymer Leuconostoc/Radish Root Ferment Filtrate PEG-8 Dimethicone Disodium Phosphate Carbomer Dextran Sodium Lactate Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Xanthan Gum Triethanolamine Sodium Phosphate Octyldodecanol Silica Sodium Propoxyhydroxypropyl Thiosulfate Silica Sodium Hydroxide Caprylyl Glycol Potassium Sorbate Sodium Benzoate Phenoxyethanol Water, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, PEG-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Caprylyl Glycol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol Dipropylene Glycol Propylene Glycol Alcohol Niacinamide Isopropyl Lauroyl Sarcosinate Pentylene Glycol CI 77891 Guanosine Mica Hydrolyzed Linseed Extract Sodium Acetylated Hyaluronate Phenylethyl Resorcinol Stearic Acid Adenosine Caffeine PEG-100 Stearate Polyacrylate Crosspolymer-6 Silica Silylate Palmitic Acid Polysorbate 80 Ammonium Polyacryloyldimethyl Taurate Limonene Tin Oxide Benzyl Alcohol Isohexadecane 3-O-Ethyl Ascorbic Acid Capryloyl Salicylic Acid Boron Nitride Ferulic Acid Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Sorbitan Oleate Myristic Acid Geraniol Octocrylene Butyl Methoxydibenzoylmethane Potas Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically). It is: You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid. This ingredient is typically used at levels between 2-20%. Regarding fungal acne: In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.