Peter Thomas Roth Retinol Fusion PM Night Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum

Peter Thomas Roth Retinol Fusion PM Night Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Peter Thomas Roth Retinol Fusion PM Night Serum versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum. This anti-aging serum is formulated around Squalane and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Cyclopentasiloxane Squalane Water Retinol Tocopheryl Acetate Ascorbyl Palmitate Bisabolol Lecithin Potassium Phosphate Pentylene Glycol Polysorbate 20 Alcohol Cyclopentasiloxane, Squalane, Water, Retinol, Tocopheryl Acetate, Ascorbyl Palmitate, Bisabolol, Lecithin, Potassium Phosphate, Pentylene Glycol, Polysorbate 20, Alcohol Dimethiconol Neopentyl Glycol Diheptanoate Dicaprylyl Carbonate Caprylic/Capric Triglyceride Phenyl Trimethicone Tetrahexyldecyl Ascorbate Tocotrienols Tocopherol Laminaria Ochroleuca Extract Avena Sativa Kernel Extract Elaeis Guineensis Oil Stearyl Glycyrrhetinate Hexylene Glycol Caprylyl Glycol Ethylhexylglycerin Phenoxyethanol Cyclopentasiloxane, Dimethiconol, Neopentyl Glycol Diheptanoate, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Squalane, Bisabolol, Tetrahexyldecyl Ascorbate, Retinol, Tocotrienols, Tocopherol, Lecithin, Laminaria Ochroleuca Extract, Avena Sativa Kernel Extract, Elaeis Guineensis Oil, Stearyl Glycyrrhetinate, Hexylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient. It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation. A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin. In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum. You'll likely see use concentrations quite low, usually 0.1-0.2%. Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin. Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy. Since D5 is volatile, it does its thing and then evaporates off the skin quickly. The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels. Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5. The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Retinol is one of the most studied anti-aging ingredients in skincare (and for good reason!). It's a form of vitamin A that your skin converts into Retinoic Acid, the active molecule that actually does the work in your cells. That conversion happens in two steps: your skin first turns Retinol into Retinaldehyde (also called Retinal), then turns Retinaldehyde into Retinoic Acid. Retinol is converted to biologically active retinoic acid via retinaldehyde by dehydrogenases in a two-step oxidation process. Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Ac