Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Prequel AM/PM Modern Moisturizer Versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer

Prequel AM/PM Modern Moisturizer Versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Detailed comparison of Prequel AM/PM Modern Moisturizer versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer. This barrier-repair moisturizer is for

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Prequel AM/PM Modern Moisturizer Versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Detailed comparison of Prequel AM/PM Modern Moisturizer versus Prequel Half & Half Peptides & Ceramides Fluid Moisturizer. This barrier-repair moisturizer is formulated around Simmondsia Chinensis Seed Oil and Squalane to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Ceramide NP and Hexapeptide-11 to strengthen the skin barrier and soften the look of wrinkles. Water Glycerin Dimethicone Simmondsia Chinensis Seed Oil Squalane Glyceryl Stearate Cetyl Alcohol Stearyl Alcohol Oleic/Linoleic/Linolenic Polyglycerides Ceramide NP Polyglyceryl-6 Laurate Polyglyceryl-6 Oleate Saccharide Isomerate Lecithin Sorbitan Oleate Hydrogenated Lecithin Linoleic Acid Sodium Hyaluronate Acetyl Heptapeptide-4 Stearic Acid Hydroxyacetophenone Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Ceramide As Ceramide Ns Ceramide EOP Ceramide AP Linolenic Acid Palmitic Acid Bacillus/Sea Salt Ferment Filtrate Isohexadecane Boron Nitride 1,2-Hexanediol Caprylyl Glycol Chlorphenesin Tocopheryl Acetate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Dicaprylyl Ether Polysorbate 80 Aluminum Starch Octenylsuccinate Sodium Hydroxide Citric Acid Phenoxyethanol Myristic Acid Tocopherol Sodium Citrate Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Oleic/Linoleic/Linolenic Polyglycerides, Ceramide NP, Polyglyceryl-6 Laurate, Polyglyceryl-6 Oleate, Saccharide Isomerate, Lecithin, Sorbitan Oleate, Hydrogenated Lecithin, Linoleic Acid, Sodium Hyaluronate, Acetyl Heptapeptide-4, Stearic Acid, Hydroxyacetophenone, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Ceramide As, Ceramide Ns, Ceramide EOP, Ceramide AP, Linolenic Acid, Palmitic Acid, Bacillus/Sea Salt Ferment Filtrate, Isohexadecane, Boron Nitride, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dicaprylyl Ether, Polysorbate 80, Aluminum Starch Octenylsuccinate, Sodium Hydroxide, Citric Acid, Phenoxyethanol, Myristic Acid, Tocopherol, Sodium Citrate Propanediol Isopropyl Myristate Ethylhexyl Olivate Hydrolyzed Rice Protein Hexapeptide-11 Matrixyl 3000 Polyglyceryl-10 Stearate Triolein Ammonium Acryloyldimethyltaurate/Vp Copolymer Glyceryl Oleate Undecane Glyceryl Dioleate Xanthan Gum Tridecane Betaine Sodium Stearoyl Glutamate Sodium Phytate Sodium PCA Sodium Lactate PCA Sodium Benzoate Serine Alanine Glycine Ethylhexyl Palmitate Butylene Glycol Ethylhexylglycerin Glutamic Acid Lysine Hcl Threonine Arginine Proline Carbomer Polysorbate 20 Water, Glycerin, Propanediol, Isopropyl Myristate, Ethylhexyl Olivate, Squalane, Hydrolyzed Rice Protein, Ceramide NP, Ceramide As, Ceramide Ns, Ceramide EOP, Ceramide AP, Hexapeptide-11, Matrixyl 3000, Polyglyceryl-10 Stearate, Triolein, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Oleate, Undecane, Hydroxyacetophenone, Glyceryl Dioleate, Caprylyl Glycol, Xanthan Gum, Tridecane, Betaine, Sodium Stearoyl Glutamate, Citric Acid, Sodium Phytate, Sodium PCA, Sodium Hydroxide, Sodium Lactate, PCA, Sodium Benzoate, Serine, Alanine, Palmitic Acid, Glycine, Hydrogenated Lecithin, Ethylhexyl Palmitate, Butylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Tocopherol, Carbomer, Polysorbate 20 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration. Ceramide AS is formally known as Ceramides 4 and 5. Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base. What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do). Low levels of Ceramide EOP have been found in people with eczema and psoriasis. Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss. In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks. You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against