Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer

Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer Detailed comparison of Prequel Half & Half Peptides & Ceramides Fluid Moisturizer versus Paula's Choice Barrier Repair Advanced Moisturizer EU. This barrier-repair moisturizer is formulated around Ceramide NP and Hexapeptide-11 to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin. Water Glycerin Propanediol Isopropyl Myristate Ethylhexyl Olivate Squalane Hydrolyzed Rice Protein Ceramide NP Ceramide As Ceramide Ns Ceramide EOP Ceramide AP Hexapeptide-11 Matrixyl 3000 Polyglyceryl-10 Stearate Triolein Ammonium Acryloyldimethyltaurate/Vp Copolymer Glyceryl Oleate Undecane Hydroxyacetophenone Glyceryl Dioleate Caprylyl Glycol Xanthan Gum Tridecane Betaine Sodium Stearoyl Glutamate Citric Acid Sodium Phytate Sodium PCA Sodium Hydroxide Sodium Lactate PCA Sodium Benzoate Serine Alanine Palmitic Acid Glycine Hydrogenated Lecithin Ethylhexyl Palmitate Butylene Glycol Phenoxyethanol Ethylhexylglycerin Glutamic Acid Lysine Hcl Threonine Arginine Proline Tocopherol Carbomer Polysorbate 20 Water, Glycerin, Propanediol, Isopropyl Myristate, Ethylhexyl Olivate, Squalane, Hydrolyzed Rice Protein, Ceramide NP, Ceramide As, Ceramide Ns, Ceramide EOP, Ceramide AP, Hexapeptide-11, Matrixyl 3000, Polyglyceryl-10 Stearate, Triolein, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Oleate, Undecane, Hydroxyacetophenone, Glyceryl Dioleate, Caprylyl Glycol, Xanthan Gum, Tridecane, Betaine, Sodium Stearoyl Glutamate, Citric Acid, Sodium Phytate, Sodium PCA, Sodium Hydroxide, Sodium Lactate, PCA, Sodium Benzoate, Serine, Alanine, Palmitic Acid, Glycine, Hydrogenated Lecithin, Ethylhexyl Palmitate, Butylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Tocopherol, Carbomer, Polysorbate 20 2,3-Butanediol Dicaprylyl Carbonate Glyceryl Stearate Cocoglycerides Ceramide Ag Sodium Hyaluronate Ceramide Ng Adenosine Butyrospermum Parkii Butter Palmitoyl Tripeptide-5 Hexylene Glycol Trehalose Cholesterol Urea Citrullus Lanatus Seed Oil Polyquaternium-51 Triacetin Sodium Polyacrylate Ethylhexyl Stearate Water, 2,3-Butanediol, Dicaprylyl Carbonate, Glycerin, Glyceryl Stearate, Cocoglycerides, Ceramide Ag, Ceramide NP, Hydroxyacetophenone, Sodium Hyaluronate, Ceramide EOP, Ceramide Ng, Ceramide AP, Adenosine, Tocopherol, Butyrospermum Parkii Butter, Palmitoyl Tripeptide-5, Hexylene Glycol, Trehalose, Cholesterol, Squalane, Sodium Phytate, Urea, Hydrogenated Lecithin, Citrullus Lanatus Seed Oil, Caprylyl Glycol, Sodium PCA, Polyquaternium-51, Triacetin, Sodium Polyacrylate, Xanthan Gum, Ethylhexyl Stearate, Phenoxyethanol, Sodium Stearoyl Glutamate, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base. What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do). Low levels of Ceramide EOP have been found in people with eczema and psoriasis. Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss. In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks. You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer impr