Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Rejuran Intensive Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream

Rejuran Intensive Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream Detailed comparison of Rejuran Intensive Eye Cream versus MediCube PDRN Pink Peptide Eye Cream. This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Tripeptide-5

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Rejuran Intensive Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream Detailed comparison of Rejuran Intensive Eye Cream versus MediCube PDRN Pink Peptide Eye Cream. This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles. This anti-aging eye moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles. Water Cetyl Alcohol Cyclopentasiloxane Dimethicone Stearic Acid Squalane Glycerin Isopropyl Palmitate Butylene Glycol Hydrogenated Polyisobutene Isodecyl Neopentanoate Niacinamide 1,2-Butanediol Calendula Officinalis Seed Oil PEG-20 Methyl Glucose Sesquistearate Stearyl Alcohol Butyrospermum Parkii Butter Pvp Methyl Glucose Sesquistearate Scutellaria Baicalensis Extract Pinus Pinaster Bark Extract Hydrolyzed DNA Panthenol Potassium Cetyl Phosphate Bisabolol Palmitoyl Tripeptide-5 Dimethicone/Vinyl Dimethicone Crosspolymer Glycyrrhiza Glabra Root Extract Morus Nigra Fruit Extract Rubus Idaeus Leaf Extract Citrus Grandis Peel Oil CI 77491 Sodium Hyaluronate Acetyl Hexapeptide-8 Ammonium Acryloyldimethyltaurate/Vp Copolymer CI 77492 Hyaluronic Acid Palmitoyl Pentapeptide-4 Tocopheryl Acetate Retinyl Palmitate Trehalose Urea Glyceryl Polyacrylate Ethylhexylglycerin Sodium Benzoate Sodium Hydroxide Adenosine Pentylene Glycol Silica Serine Hydrogenated Lecithin Algin Caprylyl Glycol Pullulan Disodium Phosphate Lavandula Angustifolia Oil Ceramide NP Oleic Acid Potassium Phosphate Citrus Aurantium Bergamia Fruit Oil Inulin Lauryl Carbamate Cholesterol Water, Cetyl Alcohol, Cyclopentasiloxane, Dimethicone, Stearic Acid, Squalane, Glycerin, Isopropyl Palmitate, Butylene Glycol, Hydrogenated Polyisobutene, Isodecyl Neopentanoate, Niacinamide, 1,2-Butanediol, Calendula Officinalis Seed Oil, PEG-20 Methyl Glucose Sesquistearate, Stearyl Alcohol, Butyrospermum Parkii Butter, Pvp, Methyl Glucose Sesquistearate, Scutellaria Baicalensis Extract, Pinus Pinaster Bark Extract, Hydrolyzed DNA, Panthenol, Potassium Cetyl Phosphate, Bisabolol, Palmitoyl Tripeptide-5, Dimethicone/Vinyl Dimethicone Crosspolymer, Glycyrrhiza Glabra Root Extract, Morus Nigra Fruit Extract, Rubus Idaeus Leaf Extract, Citrus Grandis Peel Oil, CI 77491, Sodium Hyaluronate, Acetyl Hexapeptide-8, Ammonium Acryloyldimethyltaurate/Vp Copolymer, CI 77492, Hyaluronic Acid, Palmitoyl Pentapeptide-4, Tocopheryl Acetate, Retinyl Palmitate, Trehalose, Urea, Glyceryl Polyacrylate, Ethylhexylglycerin, Sodium Benzoate, Sodium Hydroxide, Adenosine, Pentylene Glycol, Silica, Serine, Hydrogenated Lecithin, Algin, Caprylyl Glycol, Pullulan, Disodium Phosphate, Lavandula Angustifolia Oil, Ceramide NP, Oleic Acid, Potassium Phosphate, Citrus Aurantium Bergamia Fruit Oil, Inulin Lauryl Carbamate, Cholesterol Dipropylene Glycol Caprylic/Capric Triglyceride Pentaerythrityl Tetraethylhexanoate Cetearyl Alcohol Glycereth-26 Butylene Glycol Dicaprylate/Dicaprate Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate Cetearyl Olivate Sorbitan Olivate Propylene Glycol Dibenzoate 1,2-Hexanediol Glyceryl Stearate Vinyldimethicone Hydroxyacetophenone Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Sodium DNA Polyisobutene Propanediol Melia Azadirachta Leaf Extract Melia Azadirachta Flower Extract Curcuma Longa Root Extract Sorbitan Is Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with se