Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Revision Skincare Youthfull Lip Replenisher Versus PCA Skin Hyaluronic Acid Lip Booster

Revision Skincare Youthfull Lip Replenisher Versus PCA Skin Hyaluronic Acid Lip Booster Detailed comparison of Revision Skincare Youthfull Lip Replenisher versus PCA Skin Hyaluronic Acid Lip Booster. This anti-aging lip moisturizer is formulated around Sodium

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Revision Skincare Youthfull Lip Replenisher Versus PCA Skin Hyaluronic Acid Lip Booster Detailed comparison of Revision Skincare Youthfull Lip Replenisher versus PCA Skin Hyaluronic Acid Lip Booster. This anti-aging lip moisturizer is formulated around Sodium Hyaluronate and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips. Hydrogenated Polyisobutene Jojoba Esters Phenyl Trimethicone Tribehenin Helianthus Annuus Seed Oil Unsaponifiables Ethylhexyl Palmitate Butyrospermum Parkii Butter Butyrospermum Parkii Butter Unsaponifiables Sodium Hyaluronate Sucrose Cocoate Tetrahexyldecyl Ascorbate Tocopheryl Acetate Camellia Sinensis Leaf Extract Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-38 Dipalmitoyl Hydroxyproline Portulaca Pilosa Extract Caprylic/Capric Triglyceride Butylene Glycol Cetearyl Ethylhexanoate Sorbitan Isostearate Silica Dimethyl Silylate Glyceryl Caprylate Mentha Arvensis Leaf Oil Hydrogenated Polyisobutene, Jojoba Esters, Phenyl Trimethicone, Tribehenin, Helianthus Annuus Seed Oil Unsaponifiables, Ethylhexyl Palmitate, Butyrospermum Parkii Butter, Butyrospermum Parkii Butter Unsaponifiables, Sodium Hyaluronate, Sucrose Cocoate, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate, Camellia Sinensis Leaf Extract, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Dipalmitoyl Hydroxyproline, Portulaca Pilosa Extract, Caprylic/Capric Triglyceride, Butylene Glycol, Cetearyl Ethylhexanoate, Sorbitan Isostearate, Silica Dimethyl Silylate, Glyceryl Caprylate, Mentha Arvensis Leaf Oil Petrolatum Ethylene/Propylene/Styrene Copolymer Beeswax Tocopherol Aroma Ricinus Communis Seed Oil Sodium Saccharin Butylene/Ethylene/Styrene Copolymer BHT Trihydroxystearin Amorphophallus Konjac Root Powder Petrolatum, Hydrogenated Polyisobutene, Ethylene/Propylene/Styrene Copolymer, Beeswax, Ethylhexyl Palmitate, Cetearyl Ethylhexanoate, Tocopherol, Tribehenin, Aroma, Ricinus Communis Seed Oil, Sorbitan Isostearate, Sodium Saccharin, Portulaca Pilosa Extract, Butylene/Ethylene/Styrene Copolymer, BHT, Trihydroxystearin, Sucrose Cocoate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Amorphophallus Konjac Root Powder These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Cetearyl Ethylhexanoate is derived from cetearyl alcohol and sorbic acid. It is an emollient and helps hydrate the skin. Emollients form a barrier on the skin to prevent water from escaping. Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid. In cosmetics, it plays many roles: One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day. For most people, this is a well-tolerated and lightweight ingredient. This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize. Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer. In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in. Hydrogenated Polyisobutene is often used as a mineral oil replacement. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid. In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing. Human clinical data is promising, but modest: A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm. A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks. You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex. Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne. This synthetic, signal peptide has unique skin conditioning properties in that is a matrikine-mimetic compound. First of all, Palmitoyl Tripeptide-38 is a signal