Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

rhode Peptide Glazing Fluid Versus maru.derm Caffeine 5% Eye Contour Serum

rhode Peptide Glazing Fluid Versus maru.derm Caffeine 5% Eye Contour Serum Detailed comparison of rhode Peptide Glazing Fluid versus maru.derm Caffeine 5% Eye Contour Serum. This barrier-repair serum is formulated around Sclerocarya Birrea Seed Oil and Niacina

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rhode Peptide Glazing Fluid Versus maru.derm Caffeine 5% Eye Contour Serum Detailed comparison of rhode Peptide Glazing Fluid versus maru.derm Caffeine 5% Eye Contour Serum. This barrier-repair serum is formulated around Sclerocarya Birrea Seed Oil and Niacinamide to strengthen the skin barrier and soften the look of wrinkles. This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Pentapeptide-4 to soften the look of wrinkles. No concerns Water Butylene Glycol Glycerin Sclerocarya Birrea Seed Oil Niacinamide Tetradecane Capryloyl Glycerin/Sebacic Acid Copolymer Diheptyl Succinate Benzyl Alcohol Glyceryl Oleate Sucrose Palmitate Hydroxyacetophenone Carbomer Acrylates/C10-30 Alkyl Acrylate Crosspolymer Caprylyl Glycol Sodium Hydroxide Disodium Phosphate Sodium Phosphate Sodium Hyaluronate Dilauryl Thiodipropionate Acetyl Hexapeptide-8 Water, Butylene Glycol, Glycerin, Sclerocarya Birrea Seed Oil, Niacinamide, Tetradecane, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Benzyl Alcohol, Glyceryl Oleate, Sucrose Palmitate, Hydroxyacetophenone, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Sodium Hydroxide, Disodium Phosphate, Sodium Phosphate, Sodium Hyaluronate, Dilauryl Thiodipropionate, Acetyl Hexapeptide-8 Caffeine Panthenol Acetyl Tetrapeptide-5 Palmitoyl Pentapeptide-4 Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Hydrolyzed Glycosaminoglycans Hydrolyzed Hyaluronic Acid Hyaluronic Acid Sodium Hyaluronate Crosspolymer Sodium Lactate Sodium Benzoate Potassium Sorbate Sodium PCA Propanediol PCA Hydroxyethylcellulose Lactic Acid Tetrasodium EDTA Water, Caffeine, Glycerin, Panthenol, Sodium Hyaluronate, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Hydrolyzed Glycosaminoglycans, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Sodium Lactate, Sodium Benzoate, Potassium Sorbate, Sodium PCA, Propanediol, PCA, Hydroxyethylcellulose, Lactic Acid, Tetrasodium EDTA These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity. In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface. Interestingly, the size of the molecule affects its behavior: Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair. Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects. You'll typically see concentrations between 0.1-2% for this ingredient. Water. It's the most common cosmetic ingredient of all. You'll usua