Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Shiseido Essential Energy Hydrating Cream Versus Drunk Elephant Protini Polypeptide Cream

Shiseido Essential Energy Hydrating Cream Versus Drunk Elephant Protini Polypeptide Cream Detailed comparison of Shiseido Essential Energy Hydrating Cream versus Drunk Elephant Protini Polypeptide Cream. This moisturizer is formulated around Sodium Hyaluronate

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Shiseido Essential Energy Hydrating Cream Versus Drunk Elephant Protini Polypeptide Cream Detailed comparison of Shiseido Essential Energy Hydrating Cream versus Drunk Elephant Protini Polypeptide Cream. This moisturizer is formulated around Sodium Hyaluronate and Panax Ginseng Root Extract to hydrate skin. This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin. Water Dimethicone Butylene Glycol Alcohol Denat. Betaine Glycerin Isohexadecane Hydrogenated Polydecene PPG-3 Dipivalate Silica Behenyl Alcohol Stearyl Alcohol Myristyl Myristate Glyceryl Stearate Se Polysorbate 60 PEG-100 Stearate PEG/PPG-14/7 Dimethyl Ether PEG/PPG-17/4 Dimethyl Ether Phenoxyethanol Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer CI 77891 Sorbitan Tristearate Erythritol Parfum Alcohol Aminopropyl Dimethicone 2-O-Ethyl Ascorbic Acid Carbomer Trisodium EDTA Xanthan Gum Caffeine Potassium Hydroxide Isostearic Acid Sodium Metaphosphate Phytosteryl/Octyldodecyl Lauroyl Glutamate Aluminum Hydroxide Linalool Tocopherol Sodium Metabisulfite Limonene Citrus Unshiu Peel Extract Sodium Hyaluronate Angelica Keiskei Leaf/Stem Extract Ziziphus Jujuba Fruit Extract Panax Ginseng Root Extract Sodium Acetylated Hyaluronate Scutellaria Baicalensis Root Extract CI 77491 Alpinia Speciosa Leaf Extract Rosmarinus Officinalis Leaf Extract Sanguisorba Officinalis Root Extract Pyrola Incarnata Extract Water, Dimethicone, Butylene Glycol, Alcohol Denat., Betaine, Glycerin, Isohexadecane, Hydrogenated Polydecene, PPG-3 Dipivalate, Silica, Behenyl Alcohol, Stearyl Alcohol, Myristyl Myristate, Glyceryl Stearate Se, Polysorbate 60, PEG-100 Stearate, PEG/PPG-14/7 Dimethyl Ether, PEG/PPG-17/4 Dimethyl Ether, Phenoxyethanol, Dimethylacrylamide/Sodium Acryloyldimethyltaurate Crosspolymer, CI 77891, Sorbitan Tristearate, Erythritol, Parfum, Alcohol, Aminopropyl Dimethicone, 2-O-Ethyl Ascorbic Acid, Carbomer, Trisodium EDTA, Xanthan Gum, Caffeine, Potassium Hydroxide, Isostearic Acid, Sodium Metaphosphate, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Aluminum Hydroxide, Linalool, Tocopherol, Sodium Metabisulfite, Limonene, Citrus Unshiu Peel Extract, Sodium Hyaluronate, Angelica Keiskei Leaf/Stem Extract, Ziziphus Jujuba Fruit Extract, Panax Ginseng Root Extract, Sodium Acetylated Hyaluronate, Scutellaria Baicalensis Root Extract, CI 77491, Alpinia Speciosa Leaf Extract, Rosmarinus Officinalis Leaf Extract, Sanguisorba Officinalis Root Extract, Pyrola Incarnata Extract Dicaprylyl Carbonate Cetearyl Alcohol Cetearyl Olivate Sorbitan Olivate Sclerocarya Birrea Seed Oil Bacillus/Folic Acid Ferment Filtrate Extract Nymphaea Alba Root Extract Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Alanine Arginine Glycine Histidine Isoleucine Phenylalanine Proline Serine Threonine Valine Acetyl Glutamine Coconut Alkanes Coco-Caprylate/Caprate Aspartic Acid Linoleic Acid Linolenic Acid Lecithin Polyvinyl Alcohol Sodium Lactate Sodium PCA PCA Sorbitan Isostearate Polysorbate 20 Lactic Acid/Glycolic Acid Copolymer Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Isomalt 1,2-Hexanediol Caprylyl Glycol Chlorphenesin Sodium Benzoate Phenylpropanol Glyceryl Caprylate Symphytum Officinale Callus Culture Extract These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the f