Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Skin Actives Scientific High Potency EGF Serum Versus Skin Actives Scientific Collagen Serum with ROS BioNet and Apocynin

Skin Actives Scientific High Potency EGF Serum Versus Skin Actives Scientific Collagen Serum with ROS BioNet and Apocynin Detailed comparison of Skin Actives Scientific High Potency EGF Serum versus Skin Actives Scientific Collagen Serum with ROS BioNet and Ap

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Skin Actives Scientific High Potency EGF Serum Versus Skin Actives Scientific Collagen Serum with ROS BioNet and Apocynin Detailed comparison of Skin Actives Scientific High Potency EGF Serum versus Skin Actives Scientific Collagen Serum with ROS BioNet and Apocynin. This anti-aging serum is formulated around Sh-Oligopeptide-1 to soften the look of wrinkles. This anti-aging serum is formulated around Sh-Oligopeptide-1 to soften the look of wrinkles and fade the look of dark spots. No concerns Water Lactobacillus/Kelp Ferment Filtrate Glycerin Sodium PCA Sh-Oligopeptide-1 Sodium Hyaluronate Hydrolyzed Collagen Phenoxyethanol Caprylyl Glycol Sorbic Acid Water, Lactobacillus/Kelp Ferment Filtrate, Glycerin, Sodium PCA, Sh-Oligopeptide-1, Sodium Hyaluronate, Hydrolyzed Collagen, Phenoxyethanol, Caprylyl Glycol, Sorbic Acid Lactobacillus/Nereocystis Leutkeana Ferment Filtrate Magnesium Ascorbyl Phosphate Apocynin Boswellia Serrata Extract Centella Asiatica Extract Sh-Polypeptide-2 Sh-Polypeptide-77 Superoxide Dismutase Carnosine Acetyl Glucosamine Niacinamide Betulinic Acid Camellia Sinensis Leaf Extract Epigallocatechin Gallate Glutathione Polysorbate 20 Citric Acid Water, Lactobacillus/Nereocystis Leutkeana Ferment Filtrate, Glycerin, Sodium PCA, Magnesium Ascorbyl Phosphate, Hydrolyzed Collagen, Apocynin, Sodium Hyaluronate, Boswellia Serrata Extract, Centella Asiatica Extract, Sh-Polypeptide-2, Sh-Oligopeptide-1, Sh-Polypeptide-77, Superoxide Dismutase, Carnosine, Acetyl Glucosamine, Niacinamide, Betulinic Acid, Camellia Sinensis Leaf Extract, Epigallocatechin Gallate, Glutathione, Polysorbate 20, Citric Acid, Phenoxyethanol, Caprylyl Glycol, Sorbic Acid These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations. In a formula, it works mainly as a skin-conditioning and moisturizing agent. The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper. This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides. It's worth being realistic here: Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals). However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active. Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%). Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity. If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources. The results are varied. A study from 2021 f