SKIN1004 Madagascar Centella Poremizing Fresh Ampoule Versus The Ordinary Multi-Peptide + HA Serum

SKIN1004 Madagascar Centella Poremizing Fresh Ampoule Versus The Ordinary Multi-Peptide + HA Serum Detailed comparison of SKIN1004 Madagascar Centella Poremizing Fresh Ampoule versus The Ordinary Multi-Peptide + HA Serum. This smoothing ampoule is formulated around Centella Asiatica Extract and Acetyl Hexapeptide-8 to refine skin texture and soften the look of wrinkles. This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin. No concerns Water Butylene Glycol Propanediol 1,2-Hexanediol Aloe Barbadensis Leaf Extract Centella Asiatica Extract Glycereth-26 Hydroxyacetophenone Glycerin Carbomer Tromethamine Panthenol Ethylhexylglycerin Disodium EDTA Dipotassium Glycyrrhizate Ammonium Polyacryloyldimethyl Taurate Biosaccharide Gum-1 Hyaluronic Acid Hydrolyzed Hyaluronic Acid Sodium Hyaluronate Hydroxyethylcellulose Chamomilla Recutita Flower Extract Mineral Salts Tripeptide-3 Acetyl Hexapeptide-8 Acetyl Octapeptide-3 Copper Tripeptide-1 Palmitoyl Pentapeptide-4 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Tripeptide-1 Tripeptide-2 Water, Butylene Glycol, Propanediol, 1,2-Hexanediol, Aloe Barbadensis Leaf Extract, Centella Asiatica Extract, Glycereth-26, Hydroxyacetophenone, Glycerin, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Disodium EDTA, Dipotassium Glycyrrhizate, Ammonium Polyacryloyldimethyl Taurate, Biosaccharide Gum-1, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Hydroxyethylcellulose, Chamomilla Recutita Flower Extract, Mineral Salts, Tripeptide-3, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tripeptide-1, Tripeptide-2 Lactococcus Ferment Lysate Pentapeptide-18 Palmitoyl Tripeptide-38 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Citric Acid Hydroxypropyl Cyclodextrin Sodium Chloride Sodium Hydroxide Pentylene Glycol Acacia Senegal Gum Xanthan Gum Polysorbate 20 PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Trisodium Ethylenediamine Disuccinate Ethoxydiglycol Sodium Benzoate Caprylyl Glycol Phenoxyethanol Chlorphenesin Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several