SkinCeuticals Advanced RGN-6 Versus PCA Skin HydraLuxe

SkinCeuticals Advanced RGN-6 Versus PCA Skin HydraLuxe Detailed comparison of SkinCeuticals Advanced RGN-6 versus PCA Skin HydraLuxe. This barrier-repair moisturizer is formulated around Niacinamide and Squalane to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair moisturizer is formulated around Niacinamide and Butyrospermum Parkii Butter to strengthen the skin barrier and hydrate skin. Water Glycerin Ethyl Oleate Niacinamide Squalane C12-16 Alcohols Glyceryl Stearate Citrate Butyrospermum Parkii Butter Maltodextrin Ammonium Polyacryloyldimethyl Taurate Phenoxyethanol Dimethicone Palmitic Acid Hydrogenated Lecithin Cetyl Alcohol Ceratonia Siliqua Seed Extract Caprylyl Glycol 2-Oleamido-1,3-Octadecanediol Ectoin Tocopherol Eperua Falcata Bark Extract Xanthan Gum Ethylhexylglycerin Phytic Acid Adenosine Sodium Hydroxide Sodium Benzoate Acetyl Tetrapeptide-9 Citric Acid Water, Glycerin, Ethyl Oleate, Niacinamide, Squalane, C12-16 Alcohols, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Maltodextrin, Ammonium Polyacryloyldimethyl Taurate, Phenoxyethanol, Dimethicone, Palmitic Acid, Hydrogenated Lecithin, Cetyl Alcohol, Ceratonia Siliqua Seed Extract, Caprylyl Glycol, 2-Oleamido-1,3-Octadecanediol, Ectoin, Tocopherol, Eperua Falcata Bark Extract, Xanthan Gum, Ethylhexylglycerin, Phytic Acid, Adenosine, Sodium Hydroxide, Sodium Benzoate, Acetyl Tetrapeptide-9, Citric Acid Caprylic/Capric Triglyceride Cetearyl Isononanoate Pentylene Glycol Cetearyl Alcohol Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer C20-40 Alkyl Stearate Parfum Behenyl Behenate Chlorphenesin Tribehenin Cetyl Stearate Isostearyl Isostearate Potassium Cetyl Phosphate Stearic Acid Betaine Paeonia Albiflora Root Extract Cichorium Intybus Leaf Extract Hexylene Glycol Sodium Phytate Tremella Fuciformis Sporocarp Extract Acetyl Glucosamine Retinyl Palmitate Coenochloris Signiensis Extract Lecithin Lycium Barbarum Fruit Extract Water, Niacinamide, Caprylic/Capric Triglyceride, Cetearyl Isononanoate, Dimethicone, C12-16 Alcohols, Glycerin, Pentylene Glycol, Butyrospermum Parkii Butter, Maltodextrin, Squalane, Palmitic Acid, Cetearyl Alcohol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Phenoxyethanol, C20-40 Alkyl Stearate, Cetyl Alcohol, Xanthan Gum, Caprylyl Glycol, Parfum, Behenyl Behenate, Chlorphenesin, Tribehenin, Cetyl Stearate, Isostearyl Isostearate, Potassium Cetyl Phosphate, Stearic Acid, Tocopherol, Betaine, Paeonia Albiflora Root Extract, Cichorium Intybus Leaf Extract, Hexylene Glycol, Sodium Phytate, Tremella Fuciformis Sporocarp Extract, Acetyl Glucosamine, Retinyl Palmitate, Coenochloris Signiensis Extract, Lecithin, Lycium Barbarum Fruit Extract These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. This ingredient shows up on a lot of "pore-clogging" lists but there's no real evidence behind that. It doesn't even have a comedogenic rating from an actual study; the numbers you'll find online come from blogs citing other blogs. Ratings for other ingredients mostly come from a 1980s rabbit ear test. This test doesn't translate well to human skin or to real products because the ingredient sits at a much lower percentage. Some people still find it breaks them out. So if that's you, definitely trust your skin. Just know this one's based on experience and not evidence. We don't have a description for C12-16 Alcohols yet. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. Its main roles are: Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols. This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients list