Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Versus Niod Fractionated Eye Contour Concentrate Serum

SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Versus Niod Fractionated Eye Contour Concentrate Serum Detailed comparison of SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum versus Niod Fractionated Eye Contour Concentrate Serum. This anti-aging se

This source-based comparison does not add ratings or recommend a winner.

SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Versus Niod Fractionated Eye Contour Concentrate Serum Detailed comparison of SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum versus Niod Fractionated Eye Contour Concentrate Serum. This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture. This anti-aging eye moisturizer is formulated around Niacinamide and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles and fade the look of dark spots. Water Niacinamide Gluconolactone Butylene Glycol PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin Alcohol Denat. Pentylene Glycol Methyl Gluceth-20 Glycerin Potassium Hydroxide Hydroxyethylcellulose Salicylic Acid Chlorphenesin Phytic Acid Adenosine Sodium Benzoate Laminaria Digitata Extract Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetyl Hexapeptide-8 Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8 Propanediol Hydrolyzed Yeast Extract Albizia Julibrissin Bark Extract Palmitoyl Tripeptide-38 Acetyl Tetrapeptide-5 Decapeptide-22 Oligopeptide-78 Palmitoyl Decapeptide-21 Palmitoyl Hexapeptide-52 Zinc Palmitoyl Nonapeptide-14 Palmitoyl Tetrapeptide-50 Pentapeptide-18 Acetyl Hexapeptide-30 Heptapeptide-15 Palmitate Palmitoyl Heptapeptide-18 S-Mu-Conotoxin Cniiic Acetate Sodium Hyaluronate Darutoside Epigallocatechin Gallatyl Glucoside Gallyl Glucoside Ascorbyl Glucoside Zinc PCA Methylglucoside Phosphate Disodium Acetyl Glucosamine Phosphate Copper Lysinate/Prolinate Hydroxypropyl Cyclodextrin Superoxide Dismutase Escin Ascorbic Acid Ammonium Glycyrrhizate Polyglucuronic Acid Ascophyllum Nodosum Extract Asparagopsis Armata Extract Fraxinus Excelsior Bark Extract Olea Europaea Leaf Extract Polypodium Vulgare Rhizome Extract Cetraria Islandica Thallus Extract Sphagnum Magellanicum Extract Ruscus Aculeatus Root Extract Centella Asiatica Extract Calendula Officinalis Flower Extract Arginine Panthenol Hydrolyzed Rice Protein Glycine Soja Protein Hydrolyzed Wheat Protein Hydrolyzed Yeast Protein Lecithin Polyacrylate Crosspolymer-6 Xanthan Gum Cetyl Hydroxyethylcellulose Silanetriol Sodium Dextran Sulfate Sorbitol Dimethyl Isosorbide Citric Acid Glycolic Acid Lactic Acid Lactic Acid/Glycolic Acid Copolymer PPG-26-Buteth-26 Polyvinyl Alcohol PEG-40 Hydrogenated Castor Oil Propyl Gallate Potassium Sorbate Caprylyl Glycol Glyceryl Caprylate Ethylhexylglycerin Benzyl Alcohol Phenylpropanol Dehydroacetic Acid Phenoxyethanol Water, Glycerin, Butylene Glycol, Propanediol, Hydrolyzed Yeast Extract, Albizia Julibrissin Bark Extract, Niacinamide, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-38, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-5, Decapeptide-22, Oligopeptide-78, Palmitoyl Decapeptide-21, Palmitoyl Hexapeptide-52, Zinc Palmitoyl Nonapeptide-14, Palmitoyl Tetrapeptide-50, Pentapeptide-18, Acetyl Hexapeptide-30, Heptapeptide-15 Palmitate, Palmitoyl Heptapeptide-18, S-Mu-Conotoxin Cniiic Acetate, Sodium Hyaluronate, Darutoside, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Ascorbyl Glucoside, Zinc PCA, Methylglucoside Phosphate, Disodium Acetyl Glucosamine Phosphate, Copper Lysinate/Prolinate, Hydroxypropyl These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. This small molecule peptide has similar benefits to Argireline, the "botox" peptide. According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles. While this seems promising, research is lacking in proving this ingredient to be as effective as botox. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential f