Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

SkinCeuticals Triple Lipid Restore 2:4:2 Versus DRMTLGY Peptide Night Cream

SkinCeuticals Triple Lipid Restore 2:4:2 Versus DRMTLGY Peptide Night Cream Detailed comparison of SkinCeuticals Triple Lipid Restore 2:4:2 versus DRMTLGY Peptide Night Cream. This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to

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SkinCeuticals Triple Lipid Restore 2:4:2 Versus DRMTLGY Peptide Night Cream Detailed comparison of SkinCeuticals Triple Lipid Restore 2:4:2 versus DRMTLGY Peptide Night Cream. This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Dimethicone Hydrogenated Polyisobutene Glycerin Cholesterol C12-15 Alkyl Benzoate Ceramide NP Helianthus Annuus Seed Oil Unsaponifiables Bis-PEG-18 Methyl Ether Dimethyl Silane Sodium Polyacrylate PEG-10 Dimethicone Nylon-12 Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Dimethicone/PEG-10/15 Crosspolymer Phenoxyethanol Disteardimonium Hectorite Hydroxyethylpiperazine Ethane Sulfonic Acid Ammonium Polyacryloyldimethyl Taurate Chlorphenesin Caprylyl Glycol PEG/PPG-18/18 Dimethicone Propylene Carbonate Disodium EDTA Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer Adenosine Dipropylene Glycol Lavandula Angustifolia Oil Rosmarinus Officinalis Leaf Oil T-Butyl Alcohol Mentha Piperita Oil Sodium Citrate Linalool Isobutane Ceramide EOP BHT Tocopherol Limonene Water, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide NP, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene Glyceryl Stearate Propanediol Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Cetyl Alcohol PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide AP Phytosphingosine Tridecane Allantoin Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Sodium Hydroxide Sodium Lauroyl Lactylate Xanthan Gum Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. C12-15 Alkyl Benzoate is a lightweight emollient made by combinig benzoic acid with fatty alcohols that are 12-15 carbons long. In cosmetics, it plays several roles: The Cosmetic Review Expert Panel has concluded the alkyl benzoate group to be safe as used in cosmetics; it wasn't found to be a skin irritant and unlikely to be absorbed due to its low water solubility. This report recorded almost 1000 reported uses with concentrations up to 59% in leave-on products but your cosmetics will typically use 0.5-15% depending on the product. It's often called a "SPF booster": this is because it keeps UV filters properly dissolved and evenly distributed to support a sunscreen's performance. It doesn't actually raise SPF on its own. Overall, this ingredient is well tolerated. This ingredient is fungal acne safe because it is an ester of benzoic acid. Think of this ingredient as two parts stuck together: an oily part and an acid part. Malassezia only gets a meal when it can snip off a fatty acid to eat. With C12-15 Alkyl Benzoate, the acid part is benzoic acid, which isn't a fatty acid and which the yeast can't use as food. Benzoic acid is actually used as a preservative to stop yeast from growing. The oily part is a blend of C12-15 fatty alcohols but fatty alcohols in this size range can support only a little Malassezia growth (mostly for one species of Malassezia as well). In the ingredient, those alcohols stay locked inside the molecule. The yeast can only reach them by snipping the benzoate bond, and that type of bond is harder for it to cut than a normal fatty bond. So not much gets released. And whatever does get snipped comes packaged with benzoic acid, which discourages yeast growth. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base. What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do). Low levels of Ceramide EOP have been found in people with eczema and psoriasis. Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss. In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks. You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components o