Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

SkinCeuticals Triple Lipid Restore 2:4:2 Versus Skinfix Barrier+ Triple Lipid-Peptide Cream

SkinCeuticals Triple Lipid Restore 2:4:2 Versus Skinfix Barrier+ Triple Lipid-Peptide Cream Detailed comparison of SkinCeuticals Triple Lipid Restore 2:4:2 versus Skinfix Barrier+ Triple Lipid-Peptide Cream. This barrier-repair moisturizer is formulated around

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SkinCeuticals Triple Lipid Restore 2:4:2 Versus Skinfix Barrier+ Triple Lipid-Peptide Cream Detailed comparison of SkinCeuticals Triple Lipid Restore 2:4:2 versus Skinfix Barrier+ Triple Lipid-Peptide Cream. This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin. Water Dimethicone Hydrogenated Polyisobutene Glycerin Cholesterol C12-15 Alkyl Benzoate Ceramide NP Helianthus Annuus Seed Oil Unsaponifiables Bis-PEG-18 Methyl Ether Dimethyl Silane Sodium Polyacrylate PEG-10 Dimethicone Nylon-12 Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Dimethicone/PEG-10/15 Crosspolymer Phenoxyethanol Disteardimonium Hectorite Hydroxyethylpiperazine Ethane Sulfonic Acid Ammonium Polyacryloyldimethyl Taurate Chlorphenesin Caprylyl Glycol PEG/PPG-18/18 Dimethicone Propylene Carbonate Disodium EDTA Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer Adenosine Dipropylene Glycol Lavandula Angustifolia Oil Rosmarinus Officinalis Leaf Oil T-Butyl Alcohol Mentha Piperita Oil Sodium Citrate Linalool Isobutane Ceramide EOP BHT Tocopherol Limonene Water, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide NP, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene Caprylic/Capric Triglyceride Butyrospermum Parkii Butter Olus Oil Cetyl Lactate Propanediol C12-16 Alcohols Caprylyl Caprylate/Caprate Jojoba Oil/Macadamia Seed Oil Esters Glyceryl Stearate Citrate Palmitic Acid Hydrogenated Lecithin Oryza Sativa Bran Extract Dilinoleic Acid/Propanediol Copolymer Squalene Ophiopogon Japonicus Root Extract Xanthan Gum Phytosteryl Sunflowerseedate Glycine Soja Extract Pentylene Glycol Ceramide AP Hydrolyzed Rice Protein Chondrus Crispus Extract Hydrogenated Vegetable Glycerides Helianthus Annuus Extract Sodium Hyaluronate Citric Acid Phytosteryl Macadamiate Rosmarinus Officinalis Leaf Extract Aloe Barbadensis Leaf Juice Trisodium Ethylenediamine Disuccinate Phytosterols Sodium Lauroyl Lactylate Gluconolactone Phenethyl Alcohol Phytosphingosine Carbomer Potassium Sorbate Ethylhexylglycerin Sodium Benzoate Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extr These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base. What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do). Low levels of Ceramide EOP have been found in people with eczema and psoriasis. Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss. In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks. You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient. It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL). This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age. Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier. Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively. Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you hav