Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Skinfix Barrier+ Skin Barrier Restoring Gel Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer

Skinfix Barrier+ Skin Barrier Restoring Gel Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Detailed comparison of Skinfix Barrier+ Skin Barrier Restoring Gel Cream US versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer. This

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Skinfix Barrier+ Skin Barrier Restoring Gel Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Detailed comparison of Skinfix Barrier+ Skin Barrier Restoring Gel Cream US versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer. This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin. This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin. No concerns Water Squalane Propanediol Jojoba Oil/Macadamia Seed Oil Esters Triheptanoin Niacinamide Saccharide Isomerate Ammonium Acryloyldimethyltaurate/Vp Copolymer Squalene Zinc PCA Hydrolyzed Hyaluronic Acid Glycerin Camellia Sinensis Seed Extract Allantoin Phytosteryl Macadamiate Phytosterols Acetyl Glutamine Lecithin Caprylyl Glycol Amylopectin Sodium Hyaluronate Folic Acid Oligopeptide-3 Bacillus/Soybean Ferment Extract Oligopeptide-1 Oligopeptide-2 Hexapeptide-11 Tocopherol Lithothamnion Calcareum Extract Lactic Acid Glucose Acetyl Heptapeptide-4 C14-22 Alcohols C12-20 Alkyl Glucoside Ethylhexylglycerin Trisodium Ethylenediamine Disuccinate Potassium Sorbate Citric Acid Sodium Citrate Pentylene Glycol Sodium Benzoate Xanthan Gum Phenoxyethanol Water, Squalane, Propanediol, Jojoba Oil/Macadamia Seed Oil Esters, Triheptanoin, Niacinamide, Saccharide Isomerate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Squalene, Zinc PCA, Hydrolyzed Hyaluronic Acid, Glycerin, Camellia Sinensis Seed Extract, Allantoin, Phytosteryl Macadamiate, Phytosterols, Acetyl Glutamine, Lecithin, Caprylyl Glycol, Amylopectin, Sodium Hyaluronate, Folic Acid, Oligopeptide-3, Bacillus/Soybean Ferment Extract, Oligopeptide-1, Oligopeptide-2, Hexapeptide-11, Tocopherol, Lithothamnion Calcareum Extract, Lactic Acid, Glucose, Acetyl Heptapeptide-4, C14-22 Alcohols, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate, Potassium Sorbate, Citric Acid, Sodium Citrate, Pentylene Glycol, Sodium Benzoate, Xanthan Gum, Phenoxyethanol Dimethicone Pyrus Malus Fruit Extract 1,2-Hexanediol Butylene Glycol Hydroxyacetophenone Sodium Acrylates Copolymer Acrylates/C10-30 Alkyl Acrylate Crosspolymer Gigartina Stellata Extract Acetyl Sh-Hexapeptide-5 Amide Acetate Tridecapeptide-1 Sodium Phytate Hydroxypropyltrimonium Hyaluronate Cyanocobalamin Water, Dimethicone, Squalane, Glycerin, Pyrus Malus Fruit Extract, Pentylene Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Butylene Glycol, Hydroxyacetophenone, Sodium Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Gigartina Stellata Extract, Acetyl Sh-Hexapeptide-5 Amide Acetate, Tridecapeptide-1, Oligopeptide-1, Sodium Phytate, Propanediol, Lecithin, Hydroxypropyltrimonium Hyaluronate, Cyanocobalamin, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products. Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy. The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's: Due to its large molecular size, it sits on the surface of skin rather than penetrating it. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Oligopeptide-1 is another name for Epidermal Growth Factor (EGF). In a formula, EGF works as a signaling ingredient. EGF binds to receptors on your skin cells and tells keratinocytes/fibroblasts to divide, move, and rebuild the skin's support structure. A 2012 open-label study on a barley-derived EGF serum reported statistically significant improvements in fine-lines, skin texture, pore size, and uneven skin tone, with changes showing up within the first month of 2x/daily use. And a 2023 review found generally positive but modest results for growth factor products while pointing out that most trials are small, often industry-funded, and rarely test EGF on its own. So, a fair summary of this ingredient would be "promising with real mechanistic backing, but not yet large-scale proof". Concentration-wise, EGF is biologically active at very tiny amounts so finished products use it at low levels (think parts per million). Raw material supplies usually sell a pre-diluted EGF solution and recommend adding roughly 1-5%