Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

SkinMedica TNS® Advanced+ Serum Versus Alastin Restorative Eye Treatment

SkinMedica TNS® Advanced+ Serum Versus Alastin Restorative Eye Treatment Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Alastin Restorative Eye Treatment. This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Hexapeptide

This source-based comparison does not add ratings or recommend a winner.

SkinMedica TNS® Advanced+ Serum Versus Alastin Restorative Eye Treatment Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Alastin Restorative Eye Treatment. This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Hexapeptide-12 to soften the look of wrinkles and fade the look of dark spots. Water Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Glycerin Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Tocopheryl Acetate Propanediol Xanthan Gum Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Phenoxyethanol Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Caprylic/Capric Triglyceride Cetearyl Alcohol Dimethicone Jojoba Esters Cetearyl Glucoside Glyceryl Stearate Niacinamide PEG-100 Stearate Palmitoyl Hexapeptide-12 Palmitoyl Tripeptide-1 Tetrapeptide-30 Albizia Julibrissin Bark Extract Gallyl Glucoside Sodium Hyaluronate Epigallocatechin Gallatyl Glucoside Darutoside Dunaliella Salina Extract Ornithine Phospholipids Butyrospermum Parkii Butter Extract Glycolipids Betaine Tremella Fuciformis Sporocarp Extract Beta-Glucan Silica Hdi/Trimethylol Hexyllactone Crosspolymer Squalane 1,2-Hexanediol Benzyl Alcohol Dehydroacetic Acid Helianthus Annuus Seed Oil Levulinic Acid P-Anisic Acid Potassium Sorbate Sodium Benzoate Sodium Hydroxide Sorbitan Isostearate Tocopherol Caprylyl Glycol Caprylhydroxamic Acid Propyl Gallate Water, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Dimethicone, Pentylene Glycol, Jojoba Esters, Cetearyl Glucoside, Glyceryl Stearate, Niacinamide, PEG-100 Stearate, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Tetrapeptide-30, Albizia Julibrissin Bark Extract, Gallyl Glucoside, Sodium Hyaluronate, Epigallocatechin Gallatyl Glucoside, Darutoside, Dunaliella Salina Extract, Ornithine, Phospholipids, Butyrospermum Parkii Butter Extract, Glycolipids, Betaine, Tremella Fuciformis Sporocarp Extract, Beta-Glucan, Silica, Hdi/Trimethylol Hexyllactone Crosspolymer, Propanediol, Squalane, Polysorbate 20, Polyacrylate-13, Xanthan Gum, 1,2-Hexanediol, Benzyl Alcohol, Dehydroacetic Acid, Helianthus Annuus Seed Oil, Levulinic Acid, P-Anisic Acid, Potassium Sorbate, Sodium Benzoate, Sodium Hydroxide, Sorbitan Isostearate, Tocopherol, Disodium EDTA, Caprylyl Glycol, Polyisobutene, Caprylhydroxamic Acid, Phenoxyethanol, Propyl Gallate, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula: Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses. On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations. Typical use levels in a formula run about 1-5%. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large