Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

SkinMedica TNS® Advanced+ Serum Versus Dime Beauty Super Firm Serum

SkinMedica TNS® Advanced+ Serum Versus Dime Beauty Super Firm Serum Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Dime Beauty Super Firm Serum. This anti-aging serum is formulated around Palmitoyl Tripeptide-38 to soften the look of wrinkles an

This source-based comparison does not add ratings or recommend a winner.

SkinMedica TNS® Advanced+ Serum Versus Dime Beauty Super Firm Serum Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Dime Beauty Super Firm Serum. This anti-aging serum is formulated around Palmitoyl Tripeptide-38 to soften the look of wrinkles and refine skin texture. Water Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Glycerin Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Tocopheryl Acetate Propanediol Xanthan Gum Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Phenoxyethanol Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Acacia Senegal Gum Dipentaerythrityl Hexa C5-9 Acid Esters Sea Water 1,2-Hexanediol Hydrolyzed Rhizobian Gum Sodium Stearoyl Glutamate Sorbitan Laurate Dipotassium Glycyrrhizate Niacinamide Sodium Phytate Olea Europaea Fruit Unsaponifiables Palmitoyl Hexapeptide-19 Silica Hydroxyethylcellulose Acetyl Dipeptide-1 Cetyl Ester Hydrolyzed Rhodophyceae Extract Cyclodextrin Leucojum Aestivum Bulb Extract Palmitoyl Tripeptide-38 Water, Acacia Senegal Gum, Pentylene Glycol, Propanediol, Butylene Glycol, Glycerin, Dipentaerythrityl Hexa C5-9 Acid Esters, Sea Water, Pullulan, 1,2-Hexanediol, Hydroxyacetophenone, Hydrolyzed Rhizobian Gum, Xanthan Gum, Sclerotium Gum, Lecithin, Sodium Stearoyl Glutamate, Sorbitan Laurate, Dipotassium Glycyrrhizate, Niacinamide, Sodium Phytate, Olea Europaea Fruit Unsaponifiables, Palmitoyl Hexapeptide-19, Silica, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Hydrolyzed Rhodophyceae Extract, Cyclodextrin, Leucojum Aestivum Bulb Extract, Palmitoyl Tripeptide-38 Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster. As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress. Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol. This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency. You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase. Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well. An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient. So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced. Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phos