Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

SkinMedica TNS® Advanced+ Serum Versus Estée Lauder Advanced Night Repair Intense Reset Concentrate

SkinMedica TNS® Advanced+ Serum Versus Estée Lauder Advanced Night Repair Intense Reset Concentrate Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Estée Lauder Advanced Night Repair Intense Reset Concentrate. This calming serum is formulated aro

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SkinMedica TNS® Advanced+ Serum Versus Estée Lauder Advanced Night Repair Intense Reset Concentrate Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Estée Lauder Advanced Night Repair Intense Reset Concentrate. This calming serum is formulated around Lactobacillus Ferment and Resveratrol to calm redness and strengthen the skin barrier. Water Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Glycerin Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Tocopheryl Acetate Propanediol Xanthan Gum Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Phenoxyethanol Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Dimethicone Methyl Trimethicone Bis-PEG-18 Methyl Ether Dimethyl Silane Isopropyl Isostearate PPG-15 Stearyl Ether PEG-10 Dimethicone Faex Extract Tripeptide-32 Sodium Hyaluronate Crosspolymer Sodium Hyaluronate Hydrolyzed Sodium Hyaluronate Hydrolyzed Algin Lactobacillus Ferment Adansonia Digitata Seed Extract Soy Amino Acids Aminopropyl Ascorbyl Phosphate Resveratrol Algae Extract Salicylic Acid Ergothioneine Avena Sativa Kernel Extract Citrullus Lanatus Fruit Extract Laminaria Digitata Extract Lens Esculenta Fruit Extract Caffeine Sodium PCA Propylene Glycol Caprylate Triticum Vulgare Germ Extract Lavandula Angustifolia Oil Hordeum Vulgare Extract Anthemis Nobilis Flower Extract Isohexadecane Polysilicone-11 Methyldihydrojasmonate Sodium Lactate Disteardimonium Hectorite Isododecane Squalane Polyethylene Propylene Carbonate BHT Potassium Sorbate Sodium Benzoate Linalool CI 14700 CI 19140 Water, Dimethicone, Glycerin, Methyl Trimethicone, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Isopropyl Isostearate, PPG-15 Stearyl Ether, PEG-10 Dimethicone, Faex Extract, Tripeptide-32, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Algin, Lactobacillus Ferment, Adansonia Digitata Seed Extract, Soy Amino Acids, Aminopropyl Ascorbyl Phosphate, Resveratrol, Algae Extract, Salicylic Acid, Ergothioneine, Tocopheryl Acetate, Whey Protein, Avena Sativa Kernel Extract, Citrullus Lanatus Fruit Extract, Laminaria Digitata Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Caffeine, Sodium PCA, Propylene Glycol Caprylate, Triticum Vulgare Germ Extract, Lavandula Angustifolia Oil, Hordeum Vulgare Extract, Anthemis Nobilis Flower Extract, Isohexadecane, Polysilicone-11, Methyldihydrojasmonate, These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula: Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses. On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations. Typical use levels in a formula run about 1-5%. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while onl