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SkinMedica TNS® Advanced+ Serum Versus Neocutis Bio Cream Firm

SkinMedica TNS® Advanced+ Serum Versus Neocutis Bio Cream Firm Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Neocutis Bio Cream Firm. This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles and strengthen the

This source-based comparison does not add ratings or recommend a winner.

SkinMedica TNS® Advanced+ Serum Versus Neocutis Bio Cream Firm Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Neocutis Bio Cream Firm. This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles and strengthen the skin barrier. Water Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Glycerin Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Tocopheryl Acetate Propanediol Xanthan Gum Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Phenoxyethanol Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Octyldodecanol Glyceryl Stearate Decyl Oleate Propylene Glycol Stearic Acid Niacinamide Ceteareth-20 Argania Spinosa Kernel Oil Cetyl Alcohol Cutaneous Lysate Tetrapeptide-21 Palmitoyl Tripeptide-1 Acetate Sodium Lauroyl Lactylate Borago Officinalis Seed Oil Dimethicone Citric Acid Potassium Sorbate Capryloyl Carnosine Caprylyl Glycol Ceteareth-12 Cetearyl Alcohol Cetyl Palmitate Ceramide Ng Myreth-3 Myristate Carbomer Hexylene Glycol Ceramide NP Ceramide AP Phytosphingosine Cholesterol Ceramide EOP Sodium Hydroxide BHT Water, Octyldodecanol, Glyceryl Stearate, Decyl Oleate, Propylene Glycol, Glycerin, Stearic Acid, Niacinamide, Ceteareth-20, Argania Spinosa Kernel Oil, Cetyl Alcohol, Cutaneous Lysate, Tetrapeptide-21, Palmitoyl Tripeptide-1 Acetate, Sodium Lauroyl Lactylate, Borago Officinalis Seed Oil, Dimethicone, Citric Acid, Potassium Sorbate, Capryloyl Carnosine, Caprylyl Glycol, Ceteareth-12, Cetearyl Alcohol, Cetyl Palmitate, Ceramide Ng, Myreth-3 Myristate, Tocopheryl Acetate, Carbomer, Hexylene Glycol, Ceramide NP, Ceramide AP, Phytosphingosine, Cholesterol, Xanthan Gum, Ethylhexylglycerin, Ceramide EOP, Sodium Hydroxide, BHT, Disodium EDTA, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed t