SkinMedica TNS® Advanced+ Serum Versus Perricone MD High Potency Classics Face Firming Serum

SkinMedica TNS® Advanced+ Serum Versus Perricone MD High Potency Classics Face Firming Serum Detailed comparison of SkinMedica TNS® Advanced+ Serum versus Perricone MD High Potency Classics Face Firming Serum. This anti-aging serum is formulated around Thioctic Acid and Hyaluronic Acid to soften the look of wrinkles and refine skin texture. Water Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Glycerin Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Tocopheryl Acetate Propanediol Xanthan Gum Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Phenoxyethanol Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Thioctic Acid 2-Dimethylamino Ethanol Hyaluronic Acid Dimethyl Mea Isopropyl Palmitate Cetearyl Alcohol Tyrosine Glycolic Acid Dimethyl Isosorbide Glyceryl Stearate PEG-100 Stearate Urea Phosphatidylcholine Magnesium Aspartate Zinc Gluconate Acetyl Tyrosine Pyridoxine Hcl Copper Gluconate Sodium Hyaluronate BHT Ceteareth-20 Ammonium Acryloyldimethyltaurate/Vp Copolymer Dimethicone Caprylyl Glycol Zinc Sulfate Sorbic Acid Parfum Citral Citronellol Geraniol Limonene Linalool Thioctic Acid, 2-Dimethylamino Ethanol, Hyaluronic Acid, Water, Dimethyl Mea, Isopropyl Palmitate, Cetearyl Alcohol, Tyrosine, Glycolic Acid, Dimethyl Isosorbide, Propanediol, Glyceryl Stearate, PEG-100 Stearate, Urea, Phosphatidylcholine, Xanthan Gum, Magnesium Aspartate, Zinc Gluconate, Acetyl Tyrosine, Pyridoxine Hcl, Copper Gluconate, Sodium Hyaluronate, BHT, Disodium EDTA, Ceteareth-20, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Dimethicone, Caprylyl Glycol, Zinc Sulfate, Phenoxyethanol, Sorbic Acid, Parfum, Citral, Citronellol, Geraniol, Limonene, Linalool Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. It’s often used to: Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent. Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product. So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation. You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water