Skintific 10% Niacinamide Brightening Serum Versus Paula's Choice Resist Super Antioxidant Serum

Skintific 10% Niacinamide Brightening Serum Versus Paula's Choice Resist Super Antioxidant Serum Detailed comparison of Skintific 10% Niacinamide Brightening Serum versus Paula's Choice Resist Super Antioxidant Serum. This brightening serum is formulated around Niacinamide and Alpha-Arbutin to brighten dull-looking skin and fade the look of dark spots. This anti-aging serum is formulated around Tetrahexyldecyl Ascorbate and Palmitoyl Tripeptide-5 to soften the look of wrinkles and brighten dull-looking skin. Water Niacinamide Butylene Glycol Propylene Glycol PEG/PPG-14/7 Dimethyl Ether Centella Asiatica Extract Gentiana Scabra Root Extract Avena Sativa Kernel Extract Yeast Extract Crocus Sativus Flower Extract Alpha-Arbutin Ceramide NP Avena Sativa Kernel Oil Sphingolipids Ceramide As Ceramide AP Ceramide Ns Ceramide Ng 1,2-Hexanediol Bis-PEG-18 Methyl Ether Dimethyl Silane Sodium Polyacryloyldimethyl Taurate Allantoin Hydrogenated Lecithin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Pentylene Glycol Isohexadecane Tranexamic Acid Fructose Aminomethyl Propanol Propanediol Sodium Hyaluronate Disodium EDTA PEG-7 Glyceryl Cocoate Phosphatidylcholine Phytosterols Sodium Stearoyl Glutamate Hydroxyacetophenone Parfum Caprylhydroxamic Acid Soy Amino Acids Phenoxyethanol Chlorphenesin Ethylhexylglycerin Water, Niacinamide, Butylene Glycol, Propylene Glycol, PEG/PPG-14/7 Dimethyl Ether, Centella Asiatica Extract, Gentiana Scabra Root Extract, Avena Sativa Kernel Extract, Yeast Extract, Crocus Sativus Flower Extract, Alpha-Arbutin, Ceramide NP, Avena Sativa Kernel Oil, Sphingolipids, Ceramide As, Ceramide AP, Ceramide Ns, Ceramide Ng, 1,2-Hexanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacryloyldimethyl Taurate, Allantoin, Hydrogenated Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Pentylene Glycol, Isohexadecane, Tranexamic Acid, Fructose, Aminomethyl Propanol, Propanediol, Sodium Hyaluronate, Disodium EDTA, PEG-7 Glyceryl Cocoate, Phosphatidylcholine, Phytosterols, Sodium Stearoyl Glutamate, Hydroxyacetophenone, Parfum, Caprylhydroxamic Acid, Soy Amino Acids, Phenoxyethanol, Chlorphenesin, Ethylhexylglycerin Cyclopentasiloxane Dimethicone Tetrahexyldecyl Ascorbate Palmitoyl Tripeptide-5 Tocotrienols Tocopherol Ubiquinone Thioctic Acid Tocopheryl Acetate Magnesium Ascorbyl Phosphate Ferulic Acid Beta-Glucan Superoxide Dismutase Epigallocatechin Gallate Ergothioneine Glutathione Xanthophylls Glycine Soja Seed Extract Glycerin Arctostaphylos Uva Ursi Leaf Extract Lupinus Albus Seed Extract Curcuma Longa Root Elaeis Guineensis Oil Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root, Elaeis Guineensis Oil, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.