Peptide Skincare & BeautySkin science and ingredient guides

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Skintific Peptide Brightening Lip Serum Versus Essence The Super Peptide Glossy Treatment

Skintific Peptide Brightening Lip Serum Versus Essence The Super Peptide Glossy Treatment Detailed comparison of Skintific Peptide Brightening Lip Serum Clear versus Essence The Super Peptide Glossy Treatment 01 Peptacular!. This lip moisturizer is formulated

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Skintific Peptide Brightening Lip Serum Versus Essence The Super Peptide Glossy Treatment Detailed comparison of Skintific Peptide Brightening Lip Serum Clear versus Essence The Super Peptide Glossy Treatment 01 Peptacular!. This lip moisturizer is formulated around Ascorbyl Tetraisopalmitate and Palmitoyl Tripeptide-1 to hydrate lips. This anti-aging lip moisturizer is formulated around Butyrospermum Parkii Butter and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips. Petrolatum Hydrogenated Polyisobutene Octyldodecanol Polyglyceryl-2 Triisostearate Triisostearyl Citrate C10-30 Cholesterol/Lanosterol Esters Ascorbyl Tetraisopalmitate Ethylene/Propylene/Styrene Copolymer Ricinus Communis Seed Oil Squalane Dipalmitoyl Hydroxyproline Sodium Hyaluronate Butyrospermum Parkii Butter Tocopherol Hydrogenated Castor Oil Palmitoyl Tripeptide-1 Ceramide NP Ceramide Ns Ceramide As Ceramide EOP Ceramide AP Parfum Butylene/Ethylene/Styrene Copolymer Ethylhexyl Palmitate Disodium EDTA Tribehenin Sorbitan Isostearate Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Glycerin Hydrogenated Lecithin Petrolatum, Hydrogenated Polyisobutene, Octyldodecanol, Polyglyceryl-2 Triisostearate, Triisostearyl Citrate, C10-30 Cholesterol/Lanosterol Esters, Ascorbyl Tetraisopalmitate, Ethylene/Propylene/Styrene Copolymer, Ricinus Communis Seed Oil, Squalane, Dipalmitoyl Hydroxyproline, Sodium Hyaluronate, Butyrospermum Parkii Butter, Tocopherol, Hydrogenated Castor Oil, Palmitoyl Tripeptide-1, Ceramide NP, Ceramide Ns, Ceramide As, Ceramide EOP, Ceramide AP, Parfum, Butylene/Ethylene/Styrene Copolymer, Ethylhexyl Palmitate, Disodium EDTA, Tribehenin, Sorbitan Isostearate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Glycerin, Hydrogenated Lecithin Bis-Diglyceryl Polyacyladipate-2 Polybutene Dimer Dilinoleyl Dimer Dilinoleate Pentaerythrityl Tetraisostearate Sorbitan Olivate Synthetic Wax Tocopheryl Acetate Bisabolol Helianthus Annuus Seed Oil Ethylhexylglycerin Beta-Sitosterol Squalene Phenoxyethanol Aroma Bis-Diglyceryl Polyacyladipate-2, Polybutene, Butyrospermum Parkii Butter, Dimer Dilinoleyl Dimer Dilinoleate, Pentaerythrityl Tetraisostearate, Sorbitan Olivate, Synthetic Wax, Ethylhexyl Palmitate, Tocopheryl Acetate, Bisabolol, Helianthus Annuus Seed Oil, Tocopherol, Tribehenin, Sorbitan Isostearate, Ethylhexylglycerin, Palmitoyl Tripeptide-1, Beta-Sitosterol, Squalene, Phenoxyethanol, Aroma These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid. In cosmetics, it plays many roles: One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day. For most people, this is a well-tolerated and lightweight ingredient. This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid. In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing. Human clinical data is promising, but modest: A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm. A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks. You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7