Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Skyetides Glow Advanced Peptide Serum Versus M-61 Hydraboost Serum 2.0

Skyetides Glow Advanced Peptide Serum Versus M-61 Hydraboost Serum 2.0 Detailed comparison of Skyetides Glow Advanced Peptide Serum versus M-61 Hydraboost Serum 2.0. This anti-aging serum is formulated around Acetyl Octapeptide-3 and Acetyl Hexapeptide-8 to so

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Skyetides Glow Advanced Peptide Serum Versus M-61 Hydraboost Serum 2.0 Detailed comparison of Skyetides Glow Advanced Peptide Serum versus M-61 Hydraboost Serum 2.0. This anti-aging serum is formulated around Acetyl Octapeptide-3 and Acetyl Hexapeptide-8 to soften the look of wrinkles. This hydrating serum is formulated around Hydrolyzed Sodium Hyaluronate and Acetyl Hexapeptide-8 to hydrate skin and strengthen the skin barrier. Water Glycerin Pentylene Glycol 1,2-Hexanediol Butylene Glycol Polyacrylate Crosspolymer-6 Bis(Tripeptide-1) Copper Acetate Acetyl Octapeptide-3 Carbomer Sodium Acetylated Hyaluronate Sodium Hyaluronate Polysorbate 20 Sodium Hyaluronate Crosspolymer Hydrolyzed Sodium Hyaluronate Acetyl Hexapeptide-8 Aloe Barbadensis Leaf Juice Ethylhexylglycerin Caprylyl Glycol Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Water, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Butylene Glycol, Polyacrylate Crosspolymer-6, Bis(Tripeptide-1) Copper Acetate, Acetyl Octapeptide-3, Carbomer, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Polysorbate 20, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Acetyl Hexapeptide-8, Aloe Barbadensis Leaf Juice, Ethylhexylglycerin, Caprylyl Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7 Betaine Acetyl Tetrapeptide-11 Panthenol Centella Asiatica Extract Tamarindus Indica Seed Gum Sodium Lactate Citric Acid Disodium EDTA Echinacea Angustifolia Extract Mannitol Potassium Sorbate Sodium Benzoate Phenoxyethanol Water, Betaine, Glycerin, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-11, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Panthenol, Aloe Barbadensis Leaf Juice, Centella Asiatica Extract, Tamarindus Indica Seed Gum, Sodium Lactate, Citric Acid, Pentylene Glycol, Disodium EDTA, Echinacea Angustifolia Extract, Mannitol, Carbomer, Butylene Glycol, Polysorbate 20, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf. In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes. The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing. This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin. Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury. Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C. Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base). The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with mos