Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Some By Mi Retinol Intense Advanced Triple Action Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream

Some By Mi Retinol Intense Advanced Triple Action Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream Detailed comparison of Some By Mi Retinol Intense Advanced Triple Action Eye Cream versus MediCube PDRN Pink Peptide Eye Cream. This anti-aging eye moisturi

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Some By Mi Retinol Intense Advanced Triple Action Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream Detailed comparison of Some By Mi Retinol Intense Advanced Triple Action Eye Cream versus MediCube PDRN Pink Peptide Eye Cream. This anti-aging eye moisturizer is formulated around Niacinamide and Retinol to soften the look of wrinkles and fade the look of dark spots. This anti-aging eye moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles. Water Glycerin Caprylic/Capric Triglyceride Dimethicone Polysorbate 60 Niacinamide Methylpropanediol Cetyl Alcohol Polymethylsilsesquioxane Centella Asiatica Extract Dioscorea Japonica Root Extract Piper Methysticum Leaf/Root/Stem Extract Melaleuca Alternifolia Leaf Extract Panax Ginseng Berry Extract Artemisia Capillaris Extract Ganoderma Lucidum Stem Extract Chlorella Vulgaris Extract Glycine Soja Seed Extract Nymphaea Alba Flower Extract Elaeis Guineensis Oil Hydrogenated Lecithin Sodium Hyaluronate 1,2-Hexanediol Dimethicone/Vinyl Dimethicone Crosspolymer Panthenol BHT Cyclopentasiloxane Steareth-21 PEG-10 Dimethicone/Vinyl Dimethicone Crosspolymer Polyacrylamide Steareth-2 Isohexadecane Carbomer Hydroxyacetophenone C13-14 Isoparaffin Tromethamine Palmitic Acid Polyquaternium-51 Stearic Acid Polysorbate 20 Retinol 0.1% Ethylhexylglycerin Glyceryl Caprylate Tocopheryl Acetate Polyglyceryl-10 Myristate PEG-30 Dipolyhydroxystearate Hydroxyethylcellulose Glycosyl Trehalose Beta-Glucan Glyceryl Polymethacrylate Laureth-7 Butylene Glycol Disodium EDTA Hydrogenated Starch Hydrolysate Adenosine Raffinose Dipotassium Glycyrrhizate Lecithin Tocopherol Pentylene Glycol BHA Myristic Acid Tranexamic Acid Propanediol Dipropylene Glycol Disodium Phosphate Caprylyl Glycol Collagen Madecassic Acid Biosaccharide Gum-1 Asiaticoside Sodium Palmitoyl Proline Leuconostoc/Radish Root Ferment Filtrate Asiatic Acid Glutathione Retinal Madecassoside Sodium Phosphate Ferulic Acid Acetyl Hexapeptide-8 Ammonium Acryloyldimethyltaurate/Vp Copolymer Tetrahydropiperine Phloretin Arginine Parfum Water, Glycerin, Caprylic/Capric Triglyceride, Dimethicone, Polysorbate 60, Niacinamide, Methylpropanediol, Cetyl Alcohol, Polymethylsilsesquioxane, Centella Asiatica Extract, Dioscorea Japonica Root Extract, Piper Methysticum Leaf/Root/Stem Extract, Melaleuca Alternifolia Leaf Extract, Panax Ginseng Berry Extract, Artemisia Capillaris Extract, Ganoderma Lucidum Stem Extract, Chlorella Vulgaris Extract, Glycine Soja Seed Extract, Nymphaea Alba Flower Extract, Elaeis Guineensis Oil, Hydrogenated Lecithin, Sodium Hyaluronate, 1,2-Hexanediol, Dimethicone/Vinyl Dimethicone Crosspolymer, Panthenol, BHT, Cyclopentasiloxane, Steareth-21, PEG-10 Dimethicone/Vinyl Dimethicone Crosspolymer, Polyacrylamide, Steareth-2, Isohexadecane, Carbomer, Hydroxyacetophenone, C13-14 Isoparaffin, Tromethamine, Palmitic Acid, Polyquaternium-51, Stearic Acid, Polysorbate 20, Retinol 0.1%, Ethylhexylglycerin, Glyceryl Caprylate, Tocopheryl Acetate, Polyglyceryl-10 Myristate, PEG-30 Dipolyhydroxystearate, Hydroxyethylcellulose, Glycosyl Trehalose, Beta-Glucan, Glyceryl Polymethacrylate, Laureth-7, Butylene Glycol, Disodium EDTA, Hydrogenated Starch Hydrolysate, Adenosine, Raffinose, Dipotassium Glycyrrhizate, Lecithin, Tocopherol, Pentylene Glycol, BHA, Myristic Acid, Tranexamic Acid, Propanediol, Dipropylene Glycol, Disodium Phosphate, Caprylyl Glycol, Collagen, Madecassic Acid, Biosaccharide Gum-1, Asiaticosi These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it