Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Stratia Interface Cream Versus SkinMedica TNS® Advanced+ Serum

Stratia Interface Cream Versus SkinMedica TNS® Advanced+ Serum Detailed comparison of Stratia Interface Cream versus SkinMedica TNS® Advanced+ Serum. This anti-aging moisturizer is formulated around Squalane and Panthenol to soften the look of wrinkles and str

This source-based comparison does not add ratings or recommend a winner.

Stratia Interface Cream Versus SkinMedica TNS® Advanced+ Serum Detailed comparison of Stratia Interface Cream versus SkinMedica TNS® Advanced+ Serum. This anti-aging moisturizer is formulated around Squalane and Panthenol to soften the look of wrinkles and strengthen the skin barrier. Water Glycerin Squalane Hydrogenated Polydecene Panthenol Ethoxydiglycol Dimethicone Rosa Canina Fruit Oil Cetearyl Alcohol Acetyl Glutamine Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Glycyrrhiza Glabra Root Extract Allantoin Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycolic Acid Lactic Acid/Glycolic Acid Copolymer Disodium EDTA Polyacrylamide Potassium Sorbate Sodium Benzoate C13-14 Isoparaffin Polyvinyl Alcohol Methylparaben Propylparaben Laureth-7 Diazolidinyl Urea Xanthan Gum Water, Glycerin, Squalane, Hydrogenated Polydecene, Panthenol, Ethoxydiglycol, Dimethicone, Rosa Canina Fruit Oil, Cetearyl Alcohol, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Glycyrrhiza Glabra Root Extract, Allantoin, Caprylyl Glycol, Butylene Glycol, Sodium Hyaluronate, Glycolic Acid, Lactic Acid/Glycolic Acid Copolymer, Disodium EDTA, Polyacrylamide, Potassium Sorbate, Sodium Benzoate, C13-14 Isoparaffin, Polyvinyl Alcohol, Methylparaben, Propylparaben, Laureth-7, Diazolidinyl Urea, Xanthan Gum Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Tocopheryl Acetate Propanediol Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Sodium Citrate Polysorbate 20 Aminomethyl Propanol Phenoxyethanol Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Ethoxydiglycol (aka Diethylene Glycol Monoethyl Ether) is one of the cosmetic world's quiet problem solvers. In a formula, it is a solvent that dissolves tricky ingredients that don't want to mix in and helps spread ingredients evenly across your skin without leaving a greasy or sticky feeling This makes it great for hard-to-dissolve actives like vitamin C, benzoyl peroxide, and self-tanner DHA. It also has mild humectant and penetration enhancer abilities so it can help some actives absorb a little deeper. The penetration boost is backed by lab research: studies using human skin samples found it improved how well an active dissolves into the upper layer of skin rather than tearing down your skin barrier. Reviews of its mechanism also describe it interacting gently with the lipids and water in your outermost layer of skin. Just know this penetration-enhancing effect is not universal. It helps a lot in some formulas and did very little in others (so the benefit really depends on the specific product). Safety-wise, the evidence is reassuring. The Cosmetic Ingredient Review Expert Panel reviewed it and concluded it's safe for use in cosmetics and recognized it as non-irritating, non-sensitizing, and non-comedogenic in skincare. Typical leave-on skincare usage lands around 1-10%. The EU has sets caps of 2.6% in non-spray products, 10% in rinse-offs, 7% in oxidative hair dye, and 5% in non-oxidative hair dye. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from seb