Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Stratia Night Shift Versus DRMTLGY Peptide Night Cream

Stratia Night Shift Versus DRMTLGY Peptide Night Cream Detailed comparison of Stratia Night Shift versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Retinol and Squalane to soften the look of wrinkles and strengthen the

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Stratia Night Shift Versus DRMTLGY Peptide Night Cream Detailed comparison of Stratia Night Shift versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Retinol and Squalane to soften the look of wrinkles and strengthen the skin barrier. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Glycerin Squalane Sclerocarya Birrea Seed Oil Hydrogenated Polydecene Polyglyceryl-3 Methylglucose Distearate Panthenol Glyceryl Stearate Cetyl Alcohol Stearic Acid Dimethicone Hydrolyzed Centella Asiatica Extract Retinol Allantoin Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Sodium Lauroyl Lactylate Carbomer Copernicia Cerifera Cera Propanediol Sodium Cocoamphoacetate Helianthus Annuus Seed Oil Tocopherol Xanthan Gum Humulus Lupulus Extract Propylene Glycol Diazolidinyl Urea Methylparaben Propylparaben Water, Glycerin, Squalane, Sclerocarya Birrea Seed Oil, Hydrogenated Polydecene, Polyglyceryl-3 Methylglucose Distearate, Panthenol, Glyceryl Stearate, Cetyl Alcohol, Stearic Acid, Dimethicone, Hydrolyzed Centella Asiatica Extract, Retinol, Allantoin, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Carbomer, Copernicia Cerifera Cera, Propanediol, Sodium Cocoamphoacetate, Helianthus Annuus Seed Oil, Tocopherol, Xanthan Gum, Humulus Lupulus Extract, Propylene Glycol, Diazolidinyl Urea, Methylparaben, Propylparaben C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Tridecane Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Polysorbate 20 Dextran Magnesium Chloride Phenoxyethanol Disodium EDTA Sodium Hydroxide Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics. Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity. Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation. It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh. Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated. This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%. Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating. Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration. Ceramide EOP is formally known as Ceramide 1. It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer. EOP stands for a linked Ester fatty acid, a linked Omega h