Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Sunday Riley A+ High-Dose Retinol Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum

Sunday Riley A+ High-Dose Retinol Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Sunday Riley A+ High-Dose Retinol Serum versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum. This anti-aging seru

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Sunday Riley A+ High-Dose Retinol Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Sunday Riley A+ High-Dose Retinol Serum versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum. This anti-aging serum is formulated around Hydroxypinacolone Retinoate and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Propanediol Dimethyl Isosorbide Triheptanoin Dimethicone Glycerin Pentylene Glycol Hexyldecanol Disiloxane Cetyl PEG/PPG-10/1 Dimethicone Diheptyl Succinate Propylene Carbonate Hydroxypinacolone Retinoate PPG-24-Glycereth-24 Phenyl Trimethicone Retinol Ubiquinone Honey Extract Sodium Hyaluronate Crosspolymer Algae Extract Zingiber Officinale Extract Opuntia Ficus-Indica Fruit Extract Bisabolol Butyrospermum Parkii Butter Phospholipids Saccharomyces Cerevisiae Extract Lecithin Sodium Acrylates Copolymer Hydrogenated Polyisobutene 1,2-Hexanediol 4-T-Butylcyclohexanol Polyglyceryl-10 Stearate Caprylyl Glycol Helianthus Annuus Seed Oil Sorbitol Cetylhydroxyproline Palmitamide Polysilicone-11 Benzoic Acid Dehydroacetic Acid Sodium Phytate Glyceryl Polyacrylate Polysorbate 80 Hydroxyphenyl Propamidobenzoic Acid Stearic Acid Brassica Campestris Sterols Pvp Capryloyl Glycerin/Sebacic Acid Copolymer Sodium Benzoate Alcohol Potassium Phosphate Decyl Glucoside Phenoxyethanol Hexylene Glycol Potassium Sorbate Tocopherol Water, Propanediol, Dimethyl Isosorbide, Triheptanoin, Dimethicone, Glycerin, Pentylene Glycol, Hexyldecanol, Disiloxane, Cetyl PEG/PPG-10/1 Dimethicone, Diheptyl Succinate, Propylene Carbonate, Hydroxypinacolone Retinoate, PPG-24-Glycereth-24, Phenyl Trimethicone, Retinol, Ubiquinone, Honey Extract, Sodium Hyaluronate Crosspolymer, Algae Extract, Zingiber Officinale Extract, Opuntia Ficus-Indica Fruit Extract, Bisabolol, Butyrospermum Parkii Butter, Phospholipids, Saccharomyces Cerevisiae Extract, Lecithin, Sodium Acrylates Copolymer, Hydrogenated Polyisobutene, 1,2-Hexanediol, 4-T-Butylcyclohexanol, Polyglyceryl-10 Stearate, Caprylyl Glycol, Helianthus Annuus Seed Oil, Sorbitol, Cetylhydroxyproline Palmitamide, Polysilicone-11, Benzoic Acid, Dehydroacetic Acid, Sodium Phytate, Glyceryl Polyacrylate, Polysorbate 80, Hydroxyphenyl Propamidobenzoic Acid, Stearic Acid, Brassica Campestris Sterols, Pvp, Capryloyl Glycerin/Sebacic Acid Copolymer, Sodium Benzoate, Alcohol, Potassium Phosphate, Decyl Glucoside, Phenoxyethanol, Hexylene Glycol, Potassium Sorbate, Tocopherol Cyclopentasiloxane Dimethiconol Neopentyl Glycol Diheptanoate Dicaprylyl Carbonate Caprylic/Capric Triglyceride Squalane Tetrahexyldecyl Ascorbate Tocotrienols Laminaria Ochroleuca Extract Avena Sativa Kernel Extract Elaeis Guineensis Oil Stearyl Glycyrrhetinate Ethylhexylglycerin Cyclopentasiloxane, Dimethiconol, Neopentyl Glycol Diheptanoate, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Squalane, Bisabolol, Tetrahexyldecyl Ascorbate, Retinol, Tocotrienols, Tocopherol, Lecithin, Laminaria Ochroleuca Extract, Avena Sativa Kernel Extract, Elaeis Guineensis Oil, Stearyl Glycyrrhetinate, Hexylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient. It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation. A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin. In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum. You'll likely see use concentrations quite low, usually 0.1-0.2%. Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster. It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily. As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin. Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%. This ingredient is typically used at levels of 0.1-10% depending on the role it's playing. A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the