Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Tatcha The Indigo Cream Versus DRMTLGY Peptide Night Cream

Tatcha The Indigo Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Tatcha The Indigo Cream versus DRMTLGY Peptide Night Cream. This barrier-repair moisturizer is formulated around Squalane and Avena Sativa Kernel Extract to strengthen the skin b

This source-based comparison does not add ratings or recommend a winner.

Tatcha The Indigo Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Tatcha The Indigo Cream versus DRMTLGY Peptide Night Cream. This barrier-repair moisturizer is formulated around Squalane and Avena Sativa Kernel Extract to strengthen the skin barrier and calm redness. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Squalane Dimethicone Propanediol Glycerin Diisostearyl Malate Oryza Sativa Bran Wax Behenyl Alcohol Camellia Sinensis Leaf Indigofera Tinctoria Leaf Extract Polygonum Tinctorium Leaf/Stem Extract Avena Sativa Kernel Extract Sophora Japonica Flower Extract Oryza Sativa Germ Oil Cocos Nucifera Oil Inositol Sericin Tetrasodium Tetracarboxymethyl Naringeninchalcone Amorphophallus Konjac Root Powder Sodium Hyaluronate Sorbitan Tristearate Trihydroxystearin Dimethicone/Vinyl Dimethicone Crosspolymer Beheneth-20 Bis-Diglyceryl Polyacyladipate-2 Ethylhexylglycerin Butylene Glycol Sodium Dilauramidoglutamide Lysine Disodium EDTA Ethylhexyl Palmitate Sodium Acrylate/Acryloyldimethyltaurate/Dimethylacrylamide Crosspolymer Phenoxyethanol CI 77891 Mica Water, Squalane, Dimethicone, Propanediol, Glycerin, Diisostearyl Malate, Oryza Sativa Bran Wax, Behenyl Alcohol, Camellia Sinensis Leaf, Indigofera Tinctoria Leaf Extract, Polygonum Tinctorium Leaf/Stem Extract, Avena Sativa Kernel Extract, Sophora Japonica Flower Extract, Oryza Sativa Germ Oil, Cocos Nucifera Oil, Inositol, Sericin, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Amorphophallus Konjac Root Powder, Sodium Hyaluronate, Sorbitan Tristearate, Trihydroxystearin, Dimethicone/Vinyl Dimethicone Crosspolymer, Beheneth-20, Bis-Diglyceryl Polyacyladipate-2, Ethylhexylglycerin, Butylene Glycol, Sodium Dilauramidoglutamide Lysine, Disodium EDTA, Ethylhexyl Palmitate, Sodium Acrylate/Acryloyldimethyltaurate/Dimethylacrylamide Crosspolymer, Phenoxyethanol, CI 77891, Mica Glyceryl Stearate C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Cetyl Alcohol PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Tocopherol Glycol Distearate Potassium Cetyl Phosphate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Sodium Hydroxide Sodium Lauroyl Lactylate Xanthan Gum Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl La Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydratio