The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus PURITO B5 Panthenol Re-Barrier Cream

The Derma Co Skin Renew Barrier Repair Peptide Moisturizer Versus PURITO B5 Panthenol Re-Barrier Cream Detailed comparison of The Derma Co Skin Renew Barrier Repair Peptide Moisturizer versus PURITO B5 Panthenol Re-Barrier Cream. This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Panthenol to strengthen the skin barrier and calm redness. Water Propanediol Coco-Caprylate/Caprate Cetearyl Alcohol Niacinamide Betaine Cyclopentasiloxane Neopentyl Glycol Diheptanoate Isododecane Squalane 3-O-Ethyl Ascorbic Acid Ceramide NP PEG-7 Glyceryl Cocoate Phenoxyethanol Ethylhexylglycerin Glyceryl Stearate Palmitoyl Tripeptide-5 Polyacrylate-13 Polyisobutene Polysorbate 20 Glyceryl Stearate Citrate Centella Asiatica Extract Xylitylglucoside Anhydroxylitol Xylitol Sodium Hyaluronate Allantoin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Triethanolamine Sodium Gluconate Water, Propanediol, Coco-Caprylate/Caprate, Cetearyl Alcohol, Niacinamide, Betaine, Cyclopentasiloxane, Neopentyl Glycol Diheptanoate, Isododecane, Squalane, 3-O-Ethyl Ascorbic Acid, Ceramide NP, PEG-7 Glyceryl Cocoate, Phenoxyethanol, Ethylhexylglycerin, Glyceryl Stearate, Palmitoyl Tripeptide-5, Polyacrylate-13, Polyisobutene, Polysorbate 20, Glyceryl Stearate Citrate, Centella Asiatica Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Sodium Hyaluronate, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Sodium Gluconate Panthenol 10% Butylene Glycol 1,2-Hexanediol Hydrolyzed Jojoba Esters Ammonium Acryloyldimethyltaurate/Vp Copolymer Hydroxyacetophenone Tromethamine Dipotassium Glycyrrhizate Disodium EDTA Xanthan Gum Madecassoside Asiaticoside Asiatic Acid Copper Tripeptide-1 Madecassic Acid Centella Asiatica Extract, Panthenol 10%, Squalane, Butylene Glycol, Water, 1,2-Hexanediol, Niacinamide, Hydrolyzed Jojoba Esters, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyacetophenone, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Xanthan Gum, Sodium Hyaluronate, Madecassoside, Asiaticoside, Asiatic Acid, Copper Tripeptide-1, Madecassic Acid Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier. That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid. These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging. Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once. Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study. Here is the short version of what they do in the skin: So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild. Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract: Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand. Centella is one of the most easygoing actives out there. It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation. On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon. Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people. But as with any new active, a patch test is still a smart move for very reactive skin. Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams contain