Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

The Formula rx Barrier Plus Versus Dermatica Nourishing Ceramide + Peptide Moisturizer

The Formula rx Barrier Plus Versus Dermatica Nourishing Ceramide + Peptide Moisturizer Detailed comparison of The Formula rx Barrier Plus versus Dermatica Nourishing Ceramide + Peptide Moisturizer. This barrier-repair moisturizer is formulated around Sodium Hy

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The Formula rx Barrier Plus Versus Dermatica Nourishing Ceramide + Peptide Moisturizer Detailed comparison of The Formula rx Barrier Plus versus Dermatica Nourishing Ceramide + Peptide Moisturizer. This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Panthenol to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. Water Caprylic/Capric Triglyceride Glycerin Propanediol Cetearyl Alcohol Cetearyl Olivate Sorbitan Olivate Sodium Hyaluronate Panthenol Butyrospermum Parkii Butter Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Stearic Acid Sodium Lauroyl Lactylate Allantoin Xanthan Gum Butylene Glycol Carbomer Polysorbate 20 Palmitoyl Tripeptide-1 Tocopherol Palmitoyl Tetrapeptide-7 Phenoxyethanol Dimethicone Disodium EDTA Ethylhexylglycerin Water, Caprylic/Capric Triglyceride, Glycerin, Propanediol, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sodium Hyaluronate, Panthenol, Butyrospermum Parkii Butter, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Stearic Acid, Sodium Lauroyl Lactylate, Allantoin, Xanthan Gum, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Tripeptide-1, Tocopherol, Palmitoyl Tetrapeptide-7, Phenoxyethanol, Dimethicone, Disodium EDTA, Ethylhexylglycerin C12-15 Alkyl Benzoate Niacinamide Vitis Vinifera Oil Sorbitan Stearate Squalane Tocopheryl Acetate Polyacrylate Crosspolymer-6 Centella Asiatica Extract Trisodium Ethylenediamine Disuccinate Citric Acid Water, Cetearyl Alcohol, Glycerin, Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Niacinamide, Vitis Vinifera Oil, Dimethicone, Panthenol, Sorbitan Stearate, Squalane, Tocopheryl Acetate, Phenoxyethanol, Butylene Glycol, Polyacrylate Crosspolymer-6, Sodium Lauroyl Lactylate, Centella Asiatica Extract, Ethylhexylglycerin, Sodium Hyaluronate, Trisodium Ethylenediamine Disuccinate, Citric Acid, Carbomer, Ceramide NP, Ceramide AP, Phytosphingosine, Cholesterol, Polysorbate 20, Xanthan Gum, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function. You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has. The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function. Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing cera