Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

The INKEY List Tranexamic Acid Serum Versus Skintific 377 Dark Spot Serum

The INKEY List Tranexamic Acid Serum Versus Skintific 377 Dark Spot Serum Detailed comparison of The INKEY List Tranexamic Acid Serum versus Skintific 377 Dark Spot Serum. This brightening serum is formulated around Ascorbyl Glucoside and Tranexamic Acid to fa

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The INKEY List Tranexamic Acid Serum Versus Skintific 377 Dark Spot Serum Detailed comparison of The INKEY List Tranexamic Acid Serum versus Skintific 377 Dark Spot Serum. This brightening serum is formulated around Ascorbyl Glucoside and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin. This brightening serum is formulated around Niacinamide and Acetyl Glucosamine to fade the look of dark spots and brighten dull-looking skin. Water Butylene Glycol Glycerin Ascorbyl Glucoside Tranexamic Acid Euterpe Oleracea Fruit Extract 1-Methylhydantoin-2-Imide Sodium Acrylates Copolymer Phenoxyethanol Carbomer Sodium Hydroxide Cetearyl Olivate Benzyl Alcohol Sorbitan Olivate Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Lecithin Squalane Ethylhexylglycerin Sodium Gluconate Polysorbate 60 Dehydroacetic Acid Lactobacillus Ferment Sorbitan Isostearate Water, Butylene Glycol, Glycerin, Ascorbyl Glucoside, Tranexamic Acid, Euterpe Oleracea Fruit Extract, 1-Methylhydantoin-2-Imide, Sodium Acrylates Copolymer, Phenoxyethanol, Carbomer, Sodium Hydroxide, Cetearyl Olivate, Benzyl Alcohol, Sorbitan Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Lecithin, Squalane, Ethylhexylglycerin, Sodium Gluconate, Polysorbate 60, Dehydroacetic Acid, Lactobacillus Ferment, Sorbitan Isostearate Niacinamide Glycereth-26 Caprylic/Capric Triglyceride Hydroxyacetophenone 1,2-Hexanediol Acetyl Glucosamine Ectoin Simmondsia Chinensis Seed Oil Phenylethyl Resorcinol Maris Aqua Pancratium Maritimum Extract Allantoin Hydrogenated Lecithin Sodium Hyaluronate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tocopheryl Acetate Ceramide NP Diethylamino Hydroxybenzoyl Hexyl Benzoate Disodium EDTA Methylpropanediol Tocopherol Beta-Glucan Portulaca Oleracea Extract Phormidium Persicinum Extract Caprylhydroxamic Acid Fructose Hydrolyzed Rhodophyceae Extract Phosphatidylcholine Aminomethyl Propanol Polysorbate 80 Ethylhexyl Methoxycinnamate Phytosterols Sodium Stearoyl Glutamate Water, Butylene Glycol, Niacinamide, Glycerin, Glycereth-26, Caprylic/Capric Triglyceride, Hydroxyacetophenone, 1,2-Hexanediol, Acetyl Glucosamine, Ectoin, Squalane, Simmondsia Chinensis Seed Oil, Phenylethyl Resorcinol, Maris Aqua, Pancratium Maritimum Extract, Allantoin, Hydrogenated Lecithin, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Acrylates Copolymer, Tocopheryl Acetate, Ceramide NP, Lecithin, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Disodium EDTA, Methylpropanediol, Tocopherol, Beta-Glucan, Portulaca Oleracea Extract, Phormidium Persicinum Extract, Caprylhydroxamic Acid, Phenoxyethanol, Fructose, Hydrolyzed Rhodophyceae Extract, Phosphatidylcholine, Aminomethyl Propanol, Polysorbate 80, Ethylhexyl Methoxycinnamate, Phytosterols, Sodium Stearoyl Glutamate These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures ro