The INKEY List Tripeptide Plumping Lip Balm Versus The Ordinary Matrixyl 10% + HA

The INKEY List Tripeptide Plumping Lip Balm Versus The Ordinary Matrixyl 10% + HA Detailed comparison of The INKEY List Tripeptide Plumping Lip Balm Clear versus The Ordinary Matrixyl 10% + HA. This anti-aging lip moisturizer is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips. This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture. Ricinus Communis Seed Oil Hydroxystearic/Linolenic/Oleic Polyglycerides Glyceryl Rosinate Theobroma Grandiflorum Seed Butter Butyrospermum Parkii Butter Ethylhexyl Palmitate Candelilla Cera Mangifera Indica Seed Butter Orbignya Oleifera Seed Oil Squalane Cetearyl Ethylhexanoate Hydrogenated Olive Oil Salvia Hispanica Seed Oil Caprylic/Capric Triglyceride Glyceryl Behenate Olea Europaea Oil Unsaponifiables Tribehenin Sorbitan Isostearate Tocopherol Portulaca Pilosa Extract Trihydroxystearin Helianthus Annuus Seed Oil Sucrose Cocoate Brassica Alba Sprout Extract Sodium Hyaluronate Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-38 Glucomannan Ricinus Communis Seed Oil, Hydroxystearic/Linolenic/Oleic Polyglycerides, Glyceryl Rosinate, Theobroma Grandiflorum Seed Butter, Butyrospermum Parkii Butter, Ethylhexyl Palmitate, Candelilla Cera, Mangifera Indica Seed Butter, Orbignya Oleifera Seed Oil, Squalane, Cetearyl Ethylhexanoate, Hydrogenated Olive Oil, Salvia Hispanica Seed Oil, Caprylic/Capric Triglyceride, Glyceryl Behenate, Olea Europaea Oil Unsaponifiables, Tribehenin, Sorbitan Isostearate, Tocopherol, Portulaca Pilosa Extract, Trihydroxystearin, Helianthus Annuus Seed Oil, Sucrose Cocoate, Brassica Alba Sprout Extract, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Glucomannan Water Glycerin Butylene Glycol Palmitoyl Tetrapeptide-7 Hydroxypropyl Cyclodextrin PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Polyacrylate Crosspolymer-6 Trisodium Ethylenediamine Disuccinate Carbomer Polysorbate 20 Ethoxydiglycol Phenoxyethanol Chlorphenesin Water, Glycerin, Butylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Carbomer, Polysorbate 20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid. In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing. Human clinical data is promising, but modest: A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm. A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks. You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex. Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne. This synthetic, signal peptide has unique skin conditioning properties in that is a matrikine-mimetic compound. First of all, Palmitoyl Tripeptide-38 is a signal peptide; signal peptides tell the body to create more collagen. What is a matrikine-mimetic compound? This peptide has the ability to mimic matrikines in skin. Our skin created matrikines by breaking down matrix proteins into peptides. Matrikines play a role in: Though further research is needed, this ingredient seems pretty promising. In one study, women over the age of 40 with visible photoaging used a vitamin C serum with this ingredient for 56 days (15% ascorbid acid, 5 ppm palmitoyl tripeptide‐38). The results found improvement in skin roughness and skin tone. This peptide is also part of the famous Matrixyl synthe’6, a blend of ingredients that also includes glycerin, water, and hydroxypropyl cyclodextrin. Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity. In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface. Interestingly, the size of the molecule affects its behavior: Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair. Many ser