Peptide Skincare & BeautySkin science and ingredient guides

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The Ordinary Argireline Solution 10% Versus The Ordinary "Buffet" + Copper Peptides 1%

The Ordinary Argireline Solution 10% Versus The Ordinary "Buffet" + Copper Peptides 1% Detailed comparison of The Ordinary Argireline Solution 10% versus The Ordinary "Buffet" + Copper Peptides 1%. This anti-aging serum is formulated around Acetyl Hexapeptide-

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The Ordinary Argireline Solution 10% Versus The Ordinary "Buffet" + Copper Peptides 1% Detailed comparison of The Ordinary Argireline Solution 10% versus The Ordinary "Buffet" + Copper Peptides 1%. This anti-aging serum is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging serum is formulated around Copper Tripeptide-1 and Lactococcus Ferment Lysate to soften the look of wrinkles and strengthen the skin barrier. No concerns Water Propanediol Acetyl Hexapeptide-8 Trisodium Ethylenediamine Disuccinate Gellan Gum Sodium Chloride Isoceteth-20 Dimethyl Isosorbide Potassium Sorbate Phenoxyethanol Chlorphenesin Water, Propanediol, Acetyl Hexapeptide-8, Trisodium Ethylenediamine Disuccinate, Gellan Gum, Sodium Chloride, Isoceteth-20, Dimethyl Isosorbide, Potassium Sorbate, Phenoxyethanol, Chlorphenesin Glycerin Lactococcus Ferment Lysate Copper Tripeptide-1 Pentapeptide-18 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-38 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Sodium Hyaluronate Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Citric Acid Hydroxypropyl Cyclodextrin Sodium Hydroxide Butylene Glycol Pentylene Glycol Acacia Senegal Gum Xanthan Gum Carbomer Polysorbate 20 Sodium Benzoate Caprylyl Glycol Ethylhexylglycerin Water, Glycerin, Lactococcus Ferment Lysate, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. Dimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula. Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed. It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself). Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the c