Peptide Skincare & BeautySkin science and ingredient guides

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The Ordinary "Buffet" Versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex

The Ordinary "Buffet" Versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex Detailed comparison of The Ordinary "Buffet" versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex. This anti-aging serum is formulated around Lactococcus Ferment

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The Ordinary "Buffet" Versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex Detailed comparison of The Ordinary "Buffet" versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex. This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging serum is formulated around Pentapeptide-18 and Acetyl Hexapeptide-8 to soften the look of wrinkles. No concerns Water Glycerin Lactococcus Ferment Lysate Acetyl Hexapeptide-8 Pentapeptide-18 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-38 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Sodium Hyaluronate Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Citric Acid Hydroxypropyl Cyclodextrin Sodium Chloride Sodium Hydroxide Butylene Glycol Pentylene Glycol Acacia Senegal Gum Xanthan Gum Carbomer Polysorbate 20 PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Trisodium Ethylenediamine Disuccinate Ethoxydiglycol Sodium Benzoate Caprylyl Glycol Ethylhexylglycerin Phenoxyethanol Chlorphenesin Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin Betaine Palmitoyl Oligopeptide Copper Tripeptide-1 Glycosaminoglycans Propanediol Bis-PEG-8 Dimethicone Laminaria Japonica Extract Polyglutamic Acid Aminobutyric Acid Polyporus Umbellatus Extract Water, Butylene Glycol, Betaine, Pentapeptide-18, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Copper Tripeptide-1, Glycosaminoglycans, Propanediol, Bis-PEG-8 Dimethicone, Palmitoyl Tripeptide-38, Laminaria Japonica Extract, Sodium Hyaluronate Crosspolymer, Polyglutamic Acid, Aminobutyric Acid, Urea, Polyporus Umbellatus Extract, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging". "Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age. This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin. Clinical testing showed statistically significant improvements in: Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid. You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects. A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels. Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin