Peptide Skincare & BeautySkin science and ingredient guides

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The Ordinary Hyaluronic Acid 2% + B5 Versus Naturium Quadruple Hyaluronic Acid Serum 5%

The Ordinary Hyaluronic Acid 2% + B5 Versus Naturium Quadruple Hyaluronic Acid Serum 5% Detailed comparison of The Ordinary Hyaluronic Acid 2% + B5 versus Naturium Quadruple Hyaluronic Acid Serum 5%. This hydrating treatment is formulated around Sodium Hyaluro

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The Ordinary Hyaluronic Acid 2% + B5 Versus Naturium Quadruple Hyaluronic Acid Serum 5% Detailed comparison of The Ordinary Hyaluronic Acid 2% + B5 versus Naturium Quadruple Hyaluronic Acid Serum 5%. This hydrating treatment is formulated around Sodium Hyaluronate and Sodium Hyaluronate Crosspolymer to hydrate skin and strengthen the skin barrier. This hydrating serum is formulated around Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. No concerns Water Sodium Hyaluronate Pentylene Glycol Propanediol Sodium Hyaluronate Crosspolymer Panthenol Ahnfeltia Concinna Extract Glycerin Trisodium Ethylenediamine Disuccinate Citric Acid Isoceteth-20 Ethoxydiglycol Ethylhexylglycerin Hexylene Glycol 1,2-Hexanediol Phenoxyethanol Caprylyl Glycol Water, Sodium Hyaluronate, Pentylene Glycol, Propanediol, Sodium Hyaluronate Crosspolymer, Panthenol, Ahnfeltia Concinna Extract, Glycerin, Trisodium Ethylenediamine Disuccinate, Citric Acid, Isoceteth-20, Ethoxydiglycol, Ethylhexylglycerin, Hexylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Caprylyl Glycol Hydrolyzed Hyaluronic Acid Apricot Kernel Oil Polyglyceryl-6 Esters Polyglyceryl-6 Oleate Polyglyceryl-10 Oleate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Magnolol Kaempferol Tetrahexyldecyl Ascorbate Glycolipids Glycine Soja Sterols Tocopheryl Acetate Sorbitan Palmate Potassium Sorbate Sodium Hydroxide Glyceryl Polyacrylate Xanthan Gum Water, Glycerin, Propanediol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Apricot Kernel Oil Polyglyceryl-6 Esters, Polyglyceryl-6 Oleate, Caprylyl Glycol, Polyglyceryl-10 Oleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Magnolol, Kaempferol, Tetrahexyldecyl Ascorbate, Glycolipids, Glycine Soja Sterols, Tocopheryl Acetate, Phenoxyethanol, Sorbitan Palmate, Potassium Sorbate, Sodium Hydroxide, Glyceryl Polyacrylate, Xanthan Gum, Hexylene Glycol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster. It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily. As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin. Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%. This ingredient is typically used at levels of 0.1-10% depending on the role it's playing. A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylh