The Ordinary Mandelic Acid 10% + HA Versus Niod Copper Amino Isolate Serum 3 1:1 (CAIS3)

The Ordinary Mandelic Acid 10% + HA Versus Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) Detailed comparison of The Ordinary Mandelic Acid 10% + HA versus Niod Copper Amino Isolate Serum 3 1:1 (CAIS3). This smoothing serum is formulated around Mandelic Acid and Sodium Hyaluronate Crosspolymer to refine skin texture and brighten dull-looking skin. This anti-aging serum is formulated around Tripeptide-29 and Tripeptide-1 to soften the look of wrinkles. Propanediol Water Mandelic Acid Glycerin Dimethyl Isosorbide Sodium Hyaluronate Crosspolymer Tasmannia Lanceolata Fruit/Leaf Extract Pentylene Glycol Polysorbate 20 Sodium Hydroxide Ethylhexylglycerin 1,2-Hexanediol Caprylyl Glycol Propanediol, Water, Mandelic Acid, Glycerin, Dimethyl Isosorbide, Sodium Hyaluronate Crosspolymer, Tasmannia Lanceolata Fruit/Leaf Extract, Pentylene Glycol, Polysorbate 20, Sodium Hydroxide, Ethylhexylglycerin, 1,2-Hexanediol, Caprylyl Glycol Tripeptide-29 Bis(Tripeptide-1) Copper Acetate Tripeptide-1 Myristoyl Nonapeptide-3 Trifluoroacetyl Tripeptide-2 Acetyl Tetrapeptide-2 Glycogen Dextran Ethoxydiglycol Isoceteth-20 Leuconostoc/Radish Root Ferment Filtrate Phenoxyethanol Chlorphenesin Water, Glycerin, Tripeptide-29, Bis(Tripeptide-1) Copper Acetate, Tripeptide-1, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Dimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula. Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed. It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself). Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula: Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more eff