Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

The Ordinary Multi-Peptide Eye Serum Versus La Roche-Posay Hyalu B5 Eye Serum

The Ordinary Multi-Peptide Eye Serum Versus La Roche-Posay Hyalu B5 Eye Serum Detailed comparison of The Ordinary Multi-Peptide Eye Serum versus La Roche-Posay Hyalu B5 Eye Serum. This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl T

This source-based comparison does not add ratings or recommend a winner.

The Ordinary Multi-Peptide Eye Serum Versus La Roche-Posay Hyalu B5 Eye Serum Detailed comparison of The Ordinary Multi-Peptide Eye Serum versus La Roche-Posay Hyalu B5 Eye Serum. This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Tripeptide-38 to soften the look of wrinkles and fade the look of dark spots. This barrier-repair eye moisturizer is formulated around Niacinamide and Panthenol to strengthen the skin barrier and hydrate skin. No concerns Water Glycerin Butylene Glycol Propanediol Dipropylene Glycol Acetyl Glucosamine Niacinamide Palmitoyl Tripeptide-38 Acetyl Tetrapeptide-5 Myristoyl Nonapeptide-3 Dipeptide Diaminobutyroyl Benzylamide Diacetate Caffeine Epigallocatechin Gallatyl Glucoside Gallyl Glucoside Fraxinus Excelsior Bark Extract Silanetriol Arginine Pentylene Glycol Hydroxymethoxyphenyl Decanone Propyl Gallate Maltodextrin Hydroxypropyl Cyclodextrin Hydroxyethylcellulose Xanthan Gum Citric Acid Glycolic Acid Sodium Citrate Polysorbate 20 Trisodium Ethylenediamine Disuccinate Dehydroacetic Acid Ethylhexylglycerin Benzyl Alcohol Phenoxyethanol Chlorphenesin Water, Glycerin, Butylene Glycol, Propanediol, Dipropylene Glycol, Acetyl Glucosamine, Niacinamide, Palmitoyl Tripeptide-38, Acetyl Tetrapeptide-5, Myristoyl Nonapeptide-3, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Caffeine, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Fraxinus Excelsior Bark Extract, Silanetriol, Arginine, Pentylene Glycol, Hydroxymethoxyphenyl Decanone, Propyl Gallate, Maltodextrin, Hydroxypropyl Cyclodextrin, Hydroxyethylcellulose, Xanthan Gum, Citric Acid, Glycolic Acid, Sodium Citrate, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, Dehydroacetic Acid, Ethylhexylglycerin, Benzyl Alcohol, Phenoxyethanol, Chlorphenesin Hydroxyethylpiperazine Ethane Sulfonic Acid Panthenol Sodium Hyaluronate Ascorbyl Glucoside Hydroxyacetophenone Caprylyl Glycol Water, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Niacinamide, Pentylene Glycol, Panthenol, Sodium Hyaluronate, Caffeine, Ascorbyl Glucoside, Hydroxyacetophenone, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana. As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors. Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp. You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited. Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness. Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH. In skincare formulas, citric acid can: While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants. Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations. Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger. However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, el