Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

The Ordinary Multi-Peptide + HA Serum Versus By WishTrend Cera-Barrier Soothing Ampoule

The Ordinary Multi-Peptide + HA Serum Versus By WishTrend Cera-Barrier Soothing Ampoule Detailed comparison of The Ordinary Multi-Peptide + HA Serum versus By WishTrend Cera-Barrier Soothing Ampoule. This anti-aging serum is formulated around Lactococcus Ferme

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The Ordinary Multi-Peptide + HA Serum Versus By WishTrend Cera-Barrier Soothing Ampoule Detailed comparison of The Ordinary Multi-Peptide + HA Serum versus By WishTrend Cera-Barrier Soothing Ampoule. This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin. This barrier-repair ampoule is formulated around Centella Asiatica Extract and Ceramide NP to strengthen the skin barrier and calm redness. Water Glycerin Lactococcus Ferment Lysate Acetyl Hexapeptide-8 Pentapeptide-18 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-38 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Sodium Hyaluronate Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Citric Acid Hydroxypropyl Cyclodextrin Sodium Chloride Sodium Hydroxide Butylene Glycol Pentylene Glycol Acacia Senegal Gum Xanthan Gum Carbomer Polysorbate 20 PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Trisodium Ethylenediamine Disuccinate Ethoxydiglycol Sodium Benzoate Caprylyl Glycol Ethylhexylglycerin Phenoxyethanol Chlorphenesin Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin Centella Asiatica Extract 1,2-Hexanediol Propanediol Caprylic/Capric Triglyceride Squalane Ceramide NP Dicaprylyl Carbonate Hydrogenated Lecithin C14-22 Alcohols Panthenol Glyceryl Stearate Dipropylene Glycol Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer C12-20 Alkyl Glucoside Acrylates/C10-30 Alkyl Acrylate Crosspolymer Sodium Stearoyl Glutamate Helianthus Annuus Seed Oil Tromethamine Sorbitan Isostearate Pantolactone Glycine Soja Oil Tocopherol Bixa Orellana Seed Oil Copper Tripeptide-1 Palmitoyl Pentapeptide-4 Tripeptide-1 Hexapeptide-9 Nonapeptide-1 Centella Asiatica Extract, Glycerin, Butylene Glycol, 1,2-Hexanediol, Propanediol, Caprylic/Capric Triglyceride, Squalane, Ceramide NP, Dicaprylyl Carbonate, Hydrogenated Lecithin, C14-22 Alcohols, Panthenol, Glyceryl Stearate, Dipropylene Glycol, Water, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, C12-20 Alkyl Glucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Stearoyl Glutamate, Xanthan Gum, Helianthus Annuus Seed Oil, Tromethamine, Sorbitan Isostearate, Pantolactone, Glycine Soja Oil, Glucose, Tocopherol, Caprylyl Glycol, Bixa Orellana Seed Oil, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Tripeptide-1, Palmitoyl Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Ethylhexylgly These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent. Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated. It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with. Just so you know, glucose is hydrophilic (water-loving) and the stratum