The Ordinary Multi-Peptide + HA Serum Versus RNW DER. CONCENTRATE Ceramide Plus

The Ordinary Multi-Peptide + HA Serum Versus RNW DER. CONCENTRATE Ceramide Plus Detailed comparison of The Ordinary Multi-Peptide + HA Serum versus RNW DER. CONCENTRATE Ceramide Plus. This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin. This barrier-repair serum is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and hydrate skin. Water Glycerin Lactococcus Ferment Lysate Acetyl Hexapeptide-8 Pentapeptide-18 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-38 Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetylarginyltryptophyl Diphenylglycine Sodium Hyaluronate Crosspolymer Sodium Hyaluronate Allantoin Glycine Alanine Serine Valine Isoleucine Proline Threonine Histidine Phenylalanine Arginine Aspartic Acid Trehalose Fructose Glucose Maltose Urea Sodium PCA PCA Sodium Lactate Citric Acid Hydroxypropyl Cyclodextrin Sodium Chloride Sodium Hydroxide Butylene Glycol Pentylene Glycol Acacia Senegal Gum Xanthan Gum Carbomer Polysorbate 20 PPG-26-Buteth-26 PEG-40 Hydrogenated Castor Oil Trisodium Ethylenediamine Disuccinate Ethoxydiglycol Sodium Benzoate Caprylyl Glycol Ethylhexylglycerin Phenoxyethanol Chlorphenesin Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin Dipropylene Glycol Methylpropanediol Glycereth-26 1,2-Hexanediol Niacinamide Dimethicone/Vinyl Dimethicone Crosspolymer Betaine Cynara Scolymus Leaf Extract Avena Sativa Kernel Extract Ceramide NP Ceramide EOP Ceramide Ns Ceramide AP Ceramide As Nonapeptide-1 Palmitoyl Pentapeptide-4 Hexapeptide-9 Tripeptide-1 Copper Tripeptide-1 Beta Vulgaris Root Extract Eclipta Prostrata Leaf Extract Algae Extract Persea Gratissima Oil Camellia Sinensis Leaf Water Hydrogenated Lecithin Cholesterol Squalane Tocopherol Hydrolyzed Hyaluronic Acid Polyquaternium-51 Glyceryl Stearate Beta-Glucan Adenosine Fructooligosaccharides Tromethamine Glyceryl Polymethacrylate Sucrose Distearate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Silica Hydrolyzed Corn Starch Water, Dipropylene Glycol, Glycerin, Methylpropanediol, Glycereth-26, 1,2-Hexanediol, Niacinamide, Dimethicone/Vinyl Dimethicone Crosspolymer, Betaine, Cynara Scolymus Leaf Extract, Avena Sativa Kernel Extract, Ceramide NP, Ceramide EOP, Ceramide Ns, Ceramide AP, Ceramide As, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Hexapeptide-9, Tripeptide-1, Copper Tripeptide-1, Beta Vulgaris Root Extract, Eclipta Prostrata Leaf Extract, Algae Extract, Persea Gratissima Oil, Camellia Sinensis Leaf Water These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be full