Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

The Originote Acne Spot Cream Versus Paula's Choice 10% Azelaic Acid Booster

The Originote Acne Spot Cream Versus Paula's Choice 10% Azelaic Acid Booster Detailed comparison of The Originote Acne Spot Cream versus Paula's Choice 10% Azelaic Acid Booster. This acne treatment is formulated around Tranexamic Acid and Salicylic Acid to cle

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The Originote Acne Spot Cream Versus Paula's Choice 10% Azelaic Acid Booster Detailed comparison of The Originote Acne Spot Cream versus Paula's Choice 10% Azelaic Acid Booster. This acne treatment is formulated around Tranexamic Acid and Salicylic Acid to clear breakouts and calm redness. This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots. Water Cetearyl Alcohol Glycerin Butylene Glycol Tranexamic Acid Salicylic Acid Niacinamide Glyceryl Stearate PEG-100 Stearate Propanediol Ammonium Acryloyldimethyltaurate/Vp Copolymer 1,2-Hexanediol Cetearyl Glucoside Melaleuca Leucadendron Cajaput Oil Methylpropanediol Allantoin Lactobacillus/Rice Ferment Hexamidine Diisethionate Sulfur Dextrin Caprylhydroxamic Acid Acacia Senegal Gum Stephania Tetrandra Root Extract Calamine Centella Asiatica Extract Trehalose Hydroxyacetophenone Xanthan Gum Water, Cetearyl Alcohol, Glycerin, Butylene Glycol, Tranexamic Acid, Salicylic Acid, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Propanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Cetearyl Glucoside, Melaleuca Leucadendron Cajaput Oil, Methylpropanediol, Allantoin, Lactobacillus/Rice Ferment, Hexamidine Diisethionate, Sulfur, Dextrin, Caprylhydroxamic Acid, Acacia Senegal Gum, Stephania Tetrandra Root Extract, Calamine, Centella Asiatica Extract, Trehalose, Hydroxyacetophenone, Xanthan Gum Azelaic Acid C12-15 Alkyl Benzoate Caprylic/Capric Triglyceride Methyl Glucose Sesquistearate Dimethicone Adenosine Glycyrrhiza Glabra Root Extract Boerhavia Diffusa Root Extract Bisabolol Cyclopentasiloxane Sclerotium Gum Phenoxyethanol Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics. Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity. Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation. It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh. Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated. This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%. Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating. Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier. Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient. It plays several roles in a formula: Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products. Multiple assessments have found it to be non-irritating and non-sensitizing to most people. However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers. Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy. Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans. Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients. This ingre